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Showing 1–6 of 6 results
Advanced filters: Author: Eugene V. McCloskey Clear advanced filters

  • Prior assessment of fracture risk with clinical risk factors can lead to better targeted use of BMD measurements, particularly in patients aged <65 years without a previous fracture. The updated statement by the US Preventive Services Task Force on screening for osteoporosis adopts FRAX® to implement this approach.

    • Eugene McCloskey
    News & Views
    Nature Reviews Endocrinology
    Volume: 7, P: 383-384

  • Fernando Rivadeneira and colleagues in the Genetic Factors for Osteoporosis Consortium report a large-scale meta-analysis identifying new loci associated with bone mineral density (BMD) and risk of fracture. Thirty-two new loci are found to be associated with BMD, and 6 loci confer higher risk for low-trauma bone fracture.

    • Karol Estrada
    • Unnur Styrkarsdottir
    • Fernando Rivadeneira
    Research
    Nature Genetics
    Volume: 44, P: 491-501

  • New clinical guidelines incorporate the concept of absolute fracture risk, an important advance in the field of rheumatology. This Review article discusses the background, history and recent advances in the use of absolute fracture risk assessment in the management of patients with osteoporosis.

    • John A. Kanis
    • Eugene V. McCloskey
    • Anders Oden
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 425-431

  • This Review summarizes clinical effectiveness, health economics and safety data on the parathyroid hormone receptor agonists teriparatide and abaloparatide, discussing potential strategies and drug combinations to achieve best outcomes in patients with osteoporosis.

    • Nicholas Fuggle
    • René Rizzoli
    • Nicholas C. Harvey
    Reviews
    Nature Reviews Rheumatology
    Volume: 21, P: 599-611

  • High doses and long-term use of glucocorticoids lead to an important and common iatrogenic complication, glucocorticoid-induced osteoporosis. This Review outlines our current understanding of the pathogenesis of glucocorticoid-induced osteoporosis and discusses treatment options.

    • Pojchong Chotiyarnwong
    • Eugene V. McCloskey
    Reviews
    Nature Reviews Endocrinology
    Volume: 16, P: 437-447

  • In this Evidence-Based Guideline article, an international multidisciplinary working group of the European Society for Clinical and Economic Aspects of Osteoporosis, Osteoarthritis and Musculoskeletal Diseases presents recommendations for the diagnosis, monitoring and treatment of osteoporosis in men.

    • Nicholas R. Fuggle
    • Charlotte Beaudart
    • Nicholas C. Harvey
    Reviews
    Nature Reviews Rheumatology
    Volume: 20, P: 241-251