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Leukemia (4)
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Showing 1–11 of 11 results

Advanced filters: Author: F Frommlet Clear advanced filters

Rational design of potent small-molecule SMARCA2/A4 degraders acting via the recruitment of FBXO22

Degraders of SMARCA2/4 have so far relied on bivalent designs. Here, a targeted discovery campaign identified the first monovalent degraders, revealing a highly potent, selective compound that recruits FBXO22 through a covalent mechanism.

Elisia Villemure
Tom Januario
Robert L. Yauch
ResearchOpen Access03 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

The crystal and cryo-electron microscopy structure analysis of the DCAF15–DDB1–DDA1–indisulam–RBM39 complex revealed the detailed mechanism of action of indisulam-induced RBM39 degradation and defined an α-helical degron motif in RBM39.

Dirksen E. Bussiere
Lili Xie
Joshiawa Paulk
Research09 Dec 2019
Nature Chemical Biology

Volume: 16, P: 15-23
Author Correction: Structural basis of indisulam-mediated RBM39 recruitment to DCAF15 E3 ligase complex

Dirksen E. Bussiere
Lili Xie
Joshiawa Paulk
Amendments and Corrections15 Jan 2020
Nature Chemical Biology

Volume: 16, P: 361
Impact of AI-quantified fluid dynamics on visual outcomes over 5 years in patients with treatment-naïve nAMD from the FRB! registry

Philipp Fuchs
Ursula Schmidt-Erfurth
Gregor S. Reiter
ResearchOpen Access25 Sept 2025
Scientific Reports

Volume: 15, P: 1-10
APRIL limits atherosclerosis by binding to heparan sulfate proteoglycans

The heparan sulfate proteoglycan-binding cytokine APRIL has a protective role against atherosclerotic disease.

Dimitrios Tsiantoulas
Mahya Eslami
Christoph J. Binder
Research25 Aug 2021
Nature

Volume: 597, P: 92-96
Development and validation of an experimental life support system to study coral reef microbial communities

T. M. Stuij
D. F. R. Cleary
N. C. M. Gomes
ResearchOpen Access11 Sept 2024
Scientific Reports

Volume: 14, P: 1-16
Pre-emptive treatment of CMV DNAemia in paediatric stem cell transplantation: the impact of recipient and donor CMV serostatus on the incidence of CMV disease and CMV-related mortality

S Matthes-Martin
T Lion
C Peters
Research06 May 2003
Bone Marrow Transplantation

Volume: 31, P: 803-808
Quantitative monitoring of cell clones carrying point mutations in the BCR–ABL tyrosine kinase domain by ligation-dependent polymerase chain reaction (LD–PCR)

S Preuner
D Denk
T Lion
Correspondence24 Apr 2008
Leukemia

Volume: 22, P: 1956-1961
The EuroChimerism concept for a standardized approach to chimerism analysis after allogeneic stem cell transplantation

T Lion
F Watzinger
P Bader
Research07 Mar 2012
Leukemia

Volume: 26, P: 1821-1828
Lineage-specific chimaerism after stem cell transplantation in children following reduced intensity conditioning: potential predictive value of NK cell chimaerism for late graft rejection

S Matthes-Martin
T Lion
G Fritsch
Research26 Sept 2003
Leukemia

Volume: 17, P: 1934-1942
The RSD code: proposal for a nomenclature of allelic configurations in STR-PCR-based chimerism testing after allogeneic stem cell transplantation

F Watzinger
T Lion
C Steward
Correspondence01 Jun 2006
Leukemia

Volume: 20, P: 1448-1452