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Advanced filters: Author: Faith De Kuyper Clear advanced filters

Controlling nephron precursor differentiation to generate proximal-biased kidney organoids with emerging maturity

Here, the authors develop pluripotent stem cell-derived kidney organoids by mimicking in vivo proximal differentiation, providing a model to study nephron development, injury responses, and a platform for therapeutic discovery.

Jack Schnell
Zhen Miao
Nils O. Lindström
ResearchOpen Access30 Aug 2025
Nature Communications

Volume: 16, P: 1-21

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Controlling nephron precursor differentiation to generate proximal-biased kidney organoids with emerging maturity

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