The role of Kaposi's sarcoma-associated herpesvirus microRNAs in viral infection and replication remains unclear. A viral cluster containing 14 microRNAs is shown to negatively regulate viral replication by targeting the the NF-κB inhibitor IκBα and thereby decreasing NF-κB signalling.
- Xiufen Lei
- Zhiqiang Bai
- Shou-Jiang Gao