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Showing 1–7 of 7 results
Advanced filters: Author: Ferdinand W. N. M. Wit Clear advanced filters

  • The life expectancy of people living with HIV on antiretroviral therapy is close to that of the general population but wider impacts of living with HIV are not well described. Here, the authors investigate the causal effect of receiving an HIV diagnosis on labour market outcomes using data from the Netherlands.

    • Andrei Tuiu
    • Esmée Zwiers
    • Marc van der Valk
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-13

  • Elite and viremic controllers of HIV can spontaneously regulate viral replication, but some lose this ability over time. In this longitudinal cohort study, 31% of viremic and 3% of elite HIV controllers lost viral control over 17 years. Specific T-cell– related proteins distinguish controller types and predict loss years in advance.

    • Nadira Vadaq
    • Albert L. Groenendijk
    • André J. A. M. van der Ven
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-17

  • Initiating antiretroviral therapy (ART) during primary HIV-1 infection (PHI) may influence long-term viral persistence, yet its enduring effects remain unclear. Here, Pasternak and colleagues demonstrate that temporary ART started early in infection reduces HIV-1 proviral diversity and monocyte activation, and sustains lower levels of viral persistence markers, suggesting a lasting suppressive impact on the HIV-1 reservoir.

    • Alexander O. Pasternak
    • Pien M. van Paassen
    • Ben Berkhout
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-16

  • From 1980 to 2018, the levels of total and non-high-density lipoprotein cholesterol increased in low- and middle-income countries, especially in east and southeast Asia, and decreased in high-income western countries, especially those in northwestern Europe, and in central and eastern Europe.

    • Cristina Taddei
    • Bin Zhou
    • Majid Ezzati
    ResearchOpen Access
    Nature
    Volume: 582, P: 73-77