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Showing 1–4 of 4 results
Advanced filters: Author: Filippos Anagnostakis Clear advanced filters

  • Disease heterogeneity complicates precision medicine, which focuses on single conditions and ignores shared mechanisms. Here the authors introduce ‘pan-disease’ analysis using a deep learning model on multi-organ data, identifying 11 AI-derived biomarkers that reveal new therapeutic targets and pathways, enhancing patient stratification for disease risk monitoring and drug discovery.

    • Junhao Wen
    • Christos Davatzikos
    • Junhao Wen
    ResearchOpen Access
    Nature Mental Health
    Volume: 4, P: 203-230

  • Using machine learning techniques applied to multimodal UK Biobank data, Wen et al. characterize the genetic basis of the biological age gaps of individual organs, uncovering interorgan cross-talk and links between chronic diseases, lifestyle factors and biological age gaps.

    • Junhao Wen
    • Ye Ella Tian
    • Christos Davatzikos
    Research
    Nature Aging
    Volume: 4, P: 1290-1307