Nature Search

Virtual reality explored

Neuroscientists are increasingly using virtual reality to facilitate studies of animal behaviour, but whether behaviour in the virtual world mimics that in real life is a matter for debate. Here, scientists discuss the strengths and limitations of the approach.

Matthias Minderer
Christopher D. Harvey
Edvard I. Moser
News & Views11 May 2016
Nature

Volume: 533, P: 324-325
Actor–critic networks with analogue memristors mimicking reward-based learning

A framework based on actor–critic temporal difference learning and employing a biologically plausible network architecture that mimics reward-based learning on memristors and enables full in-memory training for navigation tasks is discussed.

Kevin Portner
Till Zellweger
Alexandros Emboras
ResearchOpen Access09 Dec 2025
Nature Machine Intelligence

Volume: 7, P: 1939-1953
Author Correction: Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning

Flavio Donato
Santiago Belluco Rompani
Pico Caroni
Amendments and Corrections02 May 2025
Nature

Volume: 641, P: E9
CRUSTY: a versatile web platform for the rapid analysis and visualization of high-dimensional flow cytometry data

CRUSTY is an interactive webtool for flow cytometry data analysis, offering popular algorithms and visualizations, and generating publication-quality figures in minutes. It enables users without bioinformatics expertize to mine complex datasets, supports real-time exploration, and is freely available online.

Simone Puccio
Giorgio Grillo
Enrico Lugli
ResearchOpen Access04 Sept 2023
Nature Communications

Volume: 14, P: 1-7
Minute-scale oscillatory sequences in medial entorhinal cortex

Neural population activity in the medial entorhinal cortex of mice can be organized into ultraslow oscillatory sequences, with periods extending up to the minute range.

Soledad Gonzalo Cogno
Horst A. Obenhaus
Edvard I. Moser
ResearchOpen Access20 Dec 2023
Nature

Volume: 625, P: 338-344
Author Correction: PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation

Smitha Karunakaran
Ananya Chowdhury
Pico Caroni
Amendments and Corrections16 Jul 2018
Nature Neuroscience

Volume: 21, P: 1290
Temporally matched subpopulations of selectively interconnected principal neurons in the hippocampus

The authors find that the principal hippocampal neurons consist of distinct subpopulations that show distinct neurogenesis and synaptogenesis time windows and that these neurons interconnect selectively at dentate gyrus–to-CA3 and CA3-to-CA1 synapses.

Yuichi Deguchi
Flavio Donato
Pico Caroni
Research27 Feb 2011
Nature Neuroscience

Volume: 14, P: 495-504
Goal-oriented searching mediated by ventral hippocampus early in trial-and-error learning

This study shows that a mouse's trial-and-error learning in the Morris water maze is mediated by a stereotyped sequence of hippocampus activation along its ventral-to-dorsal axis. Using anatomical or molecular lesions and a previously validated morphological readout of mossy fiber circuit refinement, the authors show that the ventral hippocampus in mice has an early role in goal-oriented learning and searching.

Sarah Ruediger
Dominique Spirig
Pico Caroni
Research23 Sept 2012
Nature Neuroscience

Volume: 15, P: 1563-1571
PV plasticity sustained through D1/5 dopamine signaling required for long-term memory consolidation

This study shows that learning-induced plasticity of local parvalbumin (PV) basket cells is specifically required for long-term, but not short to intermediate-term, memory consolidation in mice. PV plasticity depends on local D1/5 dopamine receptor signaling 12–14 h after acquisition for its continuance, ensuring enhanced sharp-wave ripple densities and memory consolidation.

Smitha Karunakaran
Ananya Chowdhury
Pico Caroni
Research25 Jan 2016
Nature Neuroscience

Volume: 19, P: 454-464
Structural plasticity upon learning: regulation and functions

Behavioural learning is accompanied by loss and gain of synapses, which is thought to be the mechanism by which circuits are altered and 'memory traces' established. Recent research, reviewed here, suggests that learning and memory events involve the rearrangement of ensembles of adjacent synapses on short stretches of dendrites.

Pico Caroni
Flavio Donato
Dominique Muller
Reviews20 Jun 2012
Nature Reviews Neuroscience

Volume: 13, P: 478-490
Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning

In adult mouse hippocampus, a learning-associated plasticity mechanism may exist that depends on the configuration of parvalbumin(PV)-expressing basket cell networks; trial and error learning initially promotes a higher fraction of cells with low PV expression, whereas learning completion promotes a higher fraction of cells with high PV expression, and these opposite configurations modulate learning and the underlying structural plasticity.

Flavio Donato
Santiago Belluco Rompani
Pico Caroni
Research11 Dec 2013
Nature

Volume: 504, P: 272-276
Skeletal muscle lncRNA profile associated with fatty acids in Nellore beef cattle

Bruna Maria Salatta
Maria Malane Magalhães Muniz
Lucia Galvão de Albuquerque
ResearchOpen Access18 Jul 2025
Scientific Reports

Volume: 15, P: 1-22
Identification of candidate lethal haplotypes and genomic association with post-natal mortality and reproductive traits in Nellore cattle

Patrícia Iana Schmidt
Lucio Flavio Macedo Mota
Lucia Galvão de Albuquerque
ResearchOpen Access27 Jun 2023
Scientific Reports

Volume: 13, P: 1-12

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