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Showing 1–5 of 5 results
Advanced filters: Author: Francesca Milletti Clear advanced filters

  • Biochemical and genetics studies identify CRL4AMBRA1 as the ubiquitin ligase that has a key role in regulating the stability of D-type cyclins during cell-cycle progression.

    • Daniele Simoneschi
    • Gergely Rona
    • Michele Pagano
    Research
    Nature
    Volume: 592, P: 789-793

  • Autophagic degradation of mitochondria (mitophagy) is a key quality control mechanism in cellular homeostasis, and its misregulation is involved in neurodegenerative diseases. Here the authors develop an optogenetic system for reversible induction of mitophagy and validate its use in cell culture and zebrafish embryos.

    • Pasquale D’Acunzo
    • Flavie Strappazzon
    • Francesco Cecconi
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13