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Showing 1–4 of 4 results

Advanced filters: Author: Francis A. Lévi Clear advanced filters

Time-of-day immunochemotherapy in nonsmall cell lung cancer: a randomized phase 3 trial

In this randomized phase 3 trial, patients with treatment-naive stage III–IV nonsmall cell lung cancer who received sintilimab or pembrolizumab in combination with chemotherapy early in the day (before 15:00 h) experienced longer progression-free survival compared with those receiving late time-of-day infusions.

Zhe Huang
Liang Zeng
Yongchang Zhang
Research02 Feb 2026
Nature Medicine

P: 1-8
Sex-, feeding-, and circadian time-dependency of P-glycoprotein expression and activity - implications for mechanistic pharmacokinetics modeling

Alper Okyar
Swati A. Kumar
Annabelle Ballesta
ResearchOpen Access19 Jul 2019
Scientific Reports

Volume: 9, P: 1-15
Why does circadian timing of administration matter for immune checkpoint inhibitors’ efficacy?

Abdoulaye Karaboué
Pasquale F. Innominato
Francis A. Lévi
ReviewsOpen Access04 Jun 2024
British Journal of Cancer

Volume: 131, P: 783-796
Pharmacogenetic determinants of outcomes on triplet hepatic artery infusion and intravenous cetuximab for liver metastases from colorectal cancer (European trial OPTILIV, NCT00852228)

Francis Lévi
Abdoulaye Karaboué
Antoinette Lemoine
ResearchOpen Access17 Aug 2017
British Journal of Cancer

Volume: 117, P: 965-973