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Scientific Reports (7)
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Showing 1–11 of 11 results

Advanced filters: Author: Fumi Kano Clear advanced filters

Establishment and phenotyping of disease model cells created by cell-resealing technique

Fumi Kano
Yoshiyuki Noguchi
Masayuki Murata
ResearchOpen Access09 Nov 2017
Scientific Reports

Volume: 7, P: 1-14
Unveiling and stratifying cell cycle-dependent drug efficacy using a single-cell PLOM-CON approach with correlation anomaly and presage protein signals

Single-cell covariation network analysis sheds light on cell cycle-dependent drug efficacy and identifies presage protein signals that predict future cell cycle arrest.

Yoshiyuki Noguchi
Rina Kunishige
Fumi Kano
ResearchOpen Access30 Oct 2025
Communications Biology

Volume: 8, P: 1-19
PPARγ-induced PARylation promotes local DNA demethylation by production of 5-hydroxymethylcytosine

Tet proteins control DNA demethylation, but how the DNA target regions are determined is unclear. Here the authors report that during adipocyte differentiation, PPARγ binds to the PPAR-response element and recruits Tet proteins, thereby inducing local DNA demethylation.

Katsunori Fujiki
Akihiro Shinoda
Masayuki Murata
Research05 Aug 2013
Nature Communications

Volume: 4, P: 1-8
Protein covariation networks for elucidating ferroptosis inducer mechanisms and potential synergistic drug targets

Using protein covariation network analysis, this study uncovers the mechanism of action for AX-53802, a new ferroptosis inducer, validating GPX4 as its direct target, and proposes combination therapies targeting FAK/Src to enhance cancer cell death.

Rina Kunishige
Yoshiyuki Noguchi
Fumi Kano
ResearchOpen Access31 Mar 2025
Communications Biology

Volume: 8, P: 1-16
LLO-mediated Cell Resealing System for Analyzing Intracellular Activity of Membrane-impermeable Biopharmaceuticals of Mid-sized Molecular Weight

Masataka Murakami
Fumi Kano
Masayuki Murata
ResearchOpen Access31 Jan 2018
Scientific Reports

Volume: 8, P: 1-13
Novel prosurvival function of Yip1A in human cervical cancer cells: constitutive activation of the IRE1 and PERK pathways of the unfolded protein response

Yuki Taguchi
Yuta Horiuchi
Masayuki Murata
ResearchOpen Access30 Mar 2017
Cell Death & Disease

Volume: 8, P: e2718
Applications of cell resealing to reconstitute microRNA loading to extracellular vesicles

Yuki Sonoda
Fumi Kano
Masayuki Murata
ResearchOpen Access03 Feb 2021
Scientific Reports

Volume: 11, P: 1-18
Changes in the asymmetric distribution of cholesterol in the plasma membrane influence streptolysin O pore formation

Fumihiko Ogasawara
Fumi Kano
Kazumitsu Ueda
ResearchOpen Access14 Mar 2019
Scientific Reports

Volume: 9, P: 1-10
Exosome-associated Shiga toxin 2 is released from cells and causes severe toxicity in mice

Miho Watanabe-Takahashi
Shinji Yamasaki
Kiyotaka Nishikawa
ResearchOpen Access17 Jul 2018
Scientific Reports

Volume: 8, P: 1-14
A prospective multicenter study on genome wide associations to ranibizumab treatment outcome for age-related macular degeneration

Kenji Yamashiro
Keisuke Mori
Nagahisa Yoshimura
ResearchOpen Access23 Aug 2017
Scientific Reports

Volume: 7, P: 1-8
Rab2A is a pivotal switch protein that promotes either secretion or ER-associated degradation of (pro)insulin in insulin-secreting cells

Taichi Sugawara
Fumi Kano
Masayuki Murata
ResearchOpen Access07 Nov 2014
Scientific Reports

Volume: 4, P: 1-14