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Retraction Note: Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ

Hanh Chi Do-Umehara
Cong Chen
Jing Liu
Amendments and Corrections07 Jan 2025
Nature Immunology

Volume: 26, P: 324
Mitochondrial one-carbon metabolism is required for TGF-β-induced glycine synthesis and fibrotic responses

De novo synthesis of amino acids supports the production of matrix proteins by fibroblasts. Here, Meliton et al. demonstrate a critical role for mitochondrial one-carbon metabolism in the production of glycine, and glycine-rich collagen proteins.

Angelo Y. Meliton
Kun Woo D. Shin
Robert B. Hamanaka
ResearchOpen Access20 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes

Ultrasensitive methods for detection of biomarkers for infectious disease are needed for diagnosing, monitoring and targeting treatment. Here the authors develop a digital assay for inflammatory markers, bacterial DNA and antibotic-resistance genes and apply it to characterise asthma patients and predict mortality from septic shock.

M. Fatih Abasıyanık
Krysta Wolfe
Savaş Tay
ResearchOpen Access25 May 2020
Nature Communications

Volume: 11, P: 1-12
Single-cell metabolic imaging reveals a SLC2A3-dependent glycolytic burst in motile endothelial cells

Wu, Harrison and colleagues visualize lactate production at subcellular resolution in migrating endothelial cells and identify hotspots of glycolytic activity, mediated by RhoA and the glucose transporter SLC2A3, that couple cellular energy metabolism with cytoskeleton remodelling and cell motility.

David Wu
Devin L. Harrison
Yun Fang
Research24 May 2021
Nature Metabolism

Volume: 3, P: 714-727
RETRACTED ARTICLE: Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-δ

Unchecked inflammation can lead to tissue damage. Liu and colleagues show that the transcription factor Miz1 recruits the histone deacetylase HDAC1 to restore repression of Cebpd transcription, which is necessary for the termination of LPS-induced inflammatory responses.

Hanh Chi Do-Umehara
Cong Chen
Jing Liu
Research24 Mar 2013
Nature Immunology

Volume: 14, P: 461-469
A metabolic strategy to reverse fibrosis?

Fibrosis is characterized by excessive extracellular matrix (ECM) production relative to catabolism. A new study shows that the fuel choice of fibroblasts impacts this balance, with glycolysis promoting ECM synthesis and fatty acid oxidation stimulating ECM degradation.

Joshua D. Rabinowitz
Gökhan M. Mutlu
News & Views07 Jan 2019
Nature Metabolism

Volume: 1, P: 12-13
HIF-1 regulates mitochondrial function in bone marrow-derived macrophages but not in tissue-resident alveolar macrophages

Parker S. Woods
Rengül Cetin-Atalay
Gökhan M. Mutlu
ResearchOpen Access04 Apr 2025
Scientific Reports

Volume: 15, P: 1-18
Intermittent hypoxia inhibits epinephrine-induced transcriptional changes in human aortic endothelial cells

Rengul Cetin-Atalay
Angelo Y. Meliton
Gökhan M. Mutlu
ResearchOpen Access13 Oct 2022
Scientific Reports

Volume: 12, P: 1-13
Particulate matter Air Pollution induces hypermethylation of the p16 promoter Via a mitochondrial ROS-JNK-DNMT1 pathway

Saul Soberanes
Angel Gonzalez
G. R. Scott Budinger
ResearchOpen Access17 Feb 2012
Scientific Reports

Volume: 2, P: 1-8

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