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Showing 1–6 of 6 results
Advanced filters: Author: Gabriel Krouk Clear advanced filters

  • Temporal control of transcriptional networks enables organisms to adapt to changing environment. Here, the authors use a scaled-up cell-based assay to identify direct targets of nitrogen-early responsive transcription factors and validate a network path mediating dynamic nitrogen signaling in Arabidopsis.

    • Matthew D. Brooks
    • Jacopo Cirrone
    • Gloria M. Coruzzi
    ResearchOpen Access
    Nature Communications
    Volume: 10, P: 1-13

  • Conventional methods cannot reveal transient transcription factors (TFs) and targets interactions. Here, Alvarez et al. capture both stable and transient TF-target interactions by time-series ChIP-seq and/or DamID-seq in a cell-based TF perturbation system and show NLP7 as a master TF to initiate a rapid nitrogen-response cascade.

    • José M. Alvarez
    • Anna-Lena Schinke
    • Gloria M. Coruzzi
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-13

  • Nitrogen and phosphorous are both major macronutrients and important signalling molecules that regulate plant growth. Here, Medici et al.show that nitrogen and phosphorous signals converge at the HRS1 transcription factor to regulate the root elongation in response to nutrient deficiency.

    • Anna Medici
    • Amy Marshall-Colon
    • Gabriel Krouk
    Research
    Nature Communications
    Volume: 6, P: 1-11

  • The nitrate signalling pathway now has a backbone. CPK calcium-dependent kinases are the long-awaited molecular link between major players in this pathway, the membrane-located nitrate transceptor NRT1.1 and the NLP transcription factors.

    • Gabriel Krouk
    News & Views
    Nature Plants
    Volume: 3, P: 1-2

  • Nitrate is a nutrient and a signal. Membrane protein NRT1.1 reflects this duality as both a nitrate transporter and sensor. A new perception mechanism has just been discovered: transcription factor NLP7 is also a nitrate sensor. Thus, two distinct but interacting systems perceive nitrate. Are there others?

    • Jordan Courrèges-Clercq
    • Gabriel Krouk
    News & Views
    Nature Plants
    Volume: 8, P: 1212-1213