Nature Search

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Reduced glomerular filtration rate (eGFR) is a hallmark of chronic kidney disease. Here, Pattaro et al. conduct a meta-analysis to discover several new loci associated with variation in eGFR and find that genes associated with eGFR loci often encode proteins potentially related to kidney development.

Cristian Pattaro
Alexander Teumer
Caroline S. Fox
ResearchOpen Access21 Jan 2016
Nature Communications

Volume: 7, P: 1-19
Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A randomized trial in patients hospitalized with COVID-19 showed no benefit and potentially increased harm associated with the use of convalescent plasma, with subgroup analyses suggesting that the antibody profile in donor plasma is critical in determining clinical outcomes.

Philippe Bégin
Jeannie Callum
Donald M. Arnold
ResearchOpen Access09 Sept 2021
Nature Medicine

Volume: 27, P: 2012-2024
A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels

Epigenetic editing of PCSK9 in the liver, designed to induce DNA methylation and silence gene expression, achieved long-lasting reductions in LDL cholesterol levels in both transgenic mice expressing the human PCSK9 gene and cynomolgus monkeys.

Frederic Tremblay
Qiang Xiong
Aron B. Jaffe
ResearchOpen Access10 Feb 2025
Nature Medicine

Volume: 31, P: 1329-1338
A saturated map of common genetic variants associated with human height

A large genome-wide association study of more than 5 million individuals reveals that 12,111 single-nucleotide polymorphisms account for nearly all the heritability of height attributable to common genetic variants.

Loïc Yengo
Sailaja Vedantam
Joel N. Hirschhorn
ResearchOpen Access12 Oct 2022
Nature

Volume: 610, P: 704-712
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Research10 Jan 2022
Nature Medicine

Volume: 28, P: 53-58
Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Philippe Bégin
Jeannie Callum
Donald M. Arnold
Amendments and CorrectionsOpen Access12 Jan 2022
Nature Medicine

Volume: 28, P: 212
Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains

The analysis of microbial genomes from human archaeological samples offers a snapshot of ancient pathogens. Here, Hodgins et al. analyze metagenomic datasets from 38 human archaeological samples and identify bacterial genomic sequences related to modern-day Clostridium tetani, encoding tetanus neurotoxins.

Harold P. Hodgins
Pengsheng Chen
Andrew C. Doxey
ResearchOpen Access06 Sept 2023
Nature Communications

Volume: 14, P: 1-15
Covariate-adjusted analysis of the Phase 3 REFLECT study of lenvatinib versus sorafenib in the treatment of unresectable hepatocellular carcinoma

Andrew Briggs
Bruno Daniele
Gabriel Tremblay
ResearchOpen Access08 Apr 2020
British Journal of Cancer

Volume: 122, P: 1754-1759
Female mice exhibit resistance to disease progression despite early pathology in a transgenic mouse model inoculated with alpha-synuclein fibrils

Sex differences in a mouse model of synucleinopathy reveals female resilience to disease progression despite early brain pathology, contrasting with accelerated disease in male mice after alpha-synuclein preformed fibril injection.

Stephanie Tullo
Janice Sung Hyun Park
M. Mallar Chakravarty
ResearchOpen Access22 Feb 2025
Communications Biology

Volume: 8, P: 1-14
Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study

Lani Cupo
Haley A. Vecchiarelli
M. Mallar Chakravarty
Research17 Sept 2025
Molecular Psychiatry

Volume: 31, P: 256-269
Latitudinal limits to the predicted increase of the peatland carbon sink with warming

Analysis of peatland carbon accumulation over the last millennium and its association with global-scale climate space indicates an ongoing carbon sink into the future, but with decreasing strength as conditions warm.

Angela V. Gallego-Sala
Dan J. Charman
Yan Zhao
Research10 Sept 2018
Nature Climate Change

Volume: 8, P: 907-913
Evaluation of the association between patent ductus arteriosus approach and neurodevelopment in extremely preterm infants

Soledad Belén Cervera
Sahar Saeed
Gabriel Altit
Research26 Jan 2024
Journal of Perinatology

Volume: 44, P: 388-395
The tumor suppression activity of E1A in HER-2/neu-overexpressing breast cancer

Joe Yujiao Chang
Weiya Xia
Mien-Chie Hung
Research06 Feb 1997
Oncogene

Volume: 14, P: 561-568
Association of meeting the 24-h movement guidelines with high blood pressure in adolescents: a cross-sectional study

Diego G. D. Christofaro
Gerson Ferrari
Javier Brazo-Sayavera
ResearchOpen Access24 Jul 2024
Scientific Reports

Volume: 14, P: 1-8
Strength of correlations in electron- and hole-doped cuprates

Copper oxide superconductors do not superconduct unless electrons or holes are added to the parent compounds. A theoretical study reveals how the electrons or holes affect the host material microscopically in an asymmetric way.

Cédric Weber
Kristjan Haule
Gabriel Kotliar
Research27 Jun 2010
Nature Physics

Volume: 6, P: 574-578
A group concept mapping study of stakeholder perspectives on digital therapeutics economic value drivers

Yoann Sapanel
L. Martin Cloutier
Dean Ho
ResearchOpen Access10 Apr 2025
npj Digital Medicine

Volume: 8, P: 1-9
History-driven population structure and asymmetric gene flow in a recovering large carnivore at the rear-edge of its European range

A. A. Karamanlidis
T. Skrbinšek
A. V. Stronen
Research11 Dec 2017
Heredity

Volume: 120, P: 168-182
Income inequality, gene expression, and brain maturation during adolescence

Nadine Parker
Angelita Pui-Yee Wong
Tomas Paus
ResearchOpen Access07 Aug 2017
Scientific Reports

Volume: 7, P: 1-11
Deciphering associations between dissolved organic molecules and bacterial communities in a pelagic marine system

Helena Osterholz
Gabriel Singer
Thorsten Dittmar
Research22 Jan 2016
The ISME Journal

Volume: 10, P: 1717-1730
Visceral fat-related systemic inflammation and the adolescent brain: a mediating role of circulating glycerophosphocholines

Catriona Syme
Stephanie Pelletier
Zdenka Pausova
Research11 Sept 2018
International Journal of Obesity

Volume: 43, P: 1223-1230
Prenatal Exposure to Maternal Cigarette Smoking and the Adolescent Cerebral Cortex

Roberto Toro
Gabriel Leonard
Tomáš Paus
Research04 Jul 2007
Neuropsychopharmacology

Volume: 33, P: 1019-1027

Search

Genetic associations at 53 loci highlight cell types and biological pathways relevant for kidney function

Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

A potent epigenetic editor targeting human PCSK9 for durable reduction of low-density lipoprotein cholesterol levels

A saturated map of common genetic variants associated with human height

Diminishing benefits of urban living for children and adolescents’ growth and development

Reply to: Concerns about estimating relative risk of death associated with convalescent plasma for COVID-19

Author Correction: Convalescent plasma for hospitalized patients with COVID-19: an open-label, randomized controlled trial

Ancient Clostridium DNA and variants of tetanus neurotoxins associated with human archaeological remains

Covariate-adjusted analysis of the Phase 3 REFLECT study of lenvatinib versus sorafenib in the treatment of unresectable hepatocellular carcinoma

Female mice exhibit resistance to disease progression despite early pathology in a transgenic mouse model inoculated with alpha-synuclein fibrils

Impact of prenatal delta-9-tetrahydrocannabinol exposure on mouse brain development: a fetal-to-adulthood magnetic resonance imaging study

Latitudinal limits to the predicted increase of the peatland carbon sink with warming

Evaluation of the association between patent ductus arteriosus approach and neurodevelopment in extremely preterm infants

The tumor suppression activity of E1A in HER-2/neu-overexpressing breast cancer

Association of meeting the 24-h movement guidelines with high blood pressure in adolescents: a cross-sectional study

Strength of correlations in electron- and hole-doped cuprates

A group concept mapping study of stakeholder perspectives on digital therapeutics economic value drivers

History-driven population structure and asymmetric gene flow in a recovering large carnivore at the rear-edge of its European range

Income inequality, gene expression, and brain maturation during adolescence

Deciphering associations between dissolved organic molecules and bacterial communities in a pelagic marine system

Visceral fat-related systemic inflammation and the adolescent brain: a mediating role of circulating glycerophosphocholines

Prenatal Exposure to Maternal Cigarette Smoking and the Adolescent Cerebral Cortex

Search

Quick links

Search

Filter By:

Search

Quick links