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Showing 1–11 of 11 results

Advanced filters: Author: Gabriela Turk Clear advanced filters

Distinct functional constraints driving conservation of the cofilin N-terminal regulatory tail

Here the authors screen a saturation mutagenesis library of the disordered N-terminal tail of the actin severing protein cofilin. Their results reveal how a key phosphorylation site can balance competing sequence constraints on function and regulation.

Joel A. Sexton
Tony Potchernikov
Benjamin E. Turk
ResearchOpen Access16 Feb 2024
Nature Communications

Volume: 15, P: 1-15
GITR triggering has limited impact on HIV-specific CD8 T-cell function but enhances HIV transcription reactivation from latently infected CD4 T-cells

Alejandro Czernikier
Lucia Baquero
Gabriela Turk
ResearchOpen Access02 Dec 2025
Scientific Reports

Volume: 15, P: 1-13
Autoregulation of the LIM kinases by their PDZ domain

LIM domain kinases are key regulators of cofilin and consequently actin severing. Here, the authors show that the LIMK PDZ domain is important for autoregulation using a conserved surface distal to the canonical PDZ-binding cleft.

Gabriela Casanova-Sepúlveda
Joel A. Sexton
Titus J. Boggon
ResearchOpen Access19 Dec 2023
Nature Communications

Volume: 14, P: 1-13
Regulation of leukocyte recruitment by the long pentraxin PTX3

Leukocytes enter inflamed tissues by initiating selectin-dependent rolling on reactive endothelia. Mantovani and colleagues show that the long pentraxin PTX3 competes for P-selectin and acts to limit neutrophil extravasation.

Livija Deban
Remo Castro Russo
Alberto Mantovani
Research07 Mar 2010
Nature Immunology

Volume: 11, P: 328-334
The psychological costs of behavioral immunity following COVID-19 diagnosis

Derek P. Spangler
Evaline Y. Li
Nina Lauharatanahirun
ResearchOpen Access30 Apr 2024
Scientific Reports

Volume: 14, P: 1-14
Th17 and Th17/Treg ratio at early HIV infection associate with protective HIV-specific CD8⁺ T-cell responses and disease progression

Juliana Falivene
Yanina Ghiglione
María Magdalena Gherardi
ResearchOpen Access23 Jun 2015
Scientific Reports

Volume: 5, P: 1-14
A multinational cross-sectional study on the prevalence and predictors of long COVID across 33 countries

Mohamed Sayed Zaazouee
Eman Ayman Nada
Mohamed Onyango
ResearchOpen Access03 Aug 2025
Scientific Reports

Volume: 15, P: 1-13
Impact of HIV-ART on the restoration of Th17 and Treg cells in blood and female genital mucosa

María Paula Caruso
Juliana Falivene
María Magdalena Gherardi
ResearchOpen Access13 Feb 2019
Scientific Reports

Volume: 9, P: 1-16
Research priorities for an HIV cure: International AIDS Society Global Scientific Strategy 2021

An effective and scalable cure strategy is a top priority for the HIV research field; this Review discusses recent advances, knowledge gaps, and priority research areas for the next 5 years.

Steven G. Deeks
Nancie Archin
Edward Nelson Kankaka
Reviews01 Dec 2021
Nature Medicine

Volume: 27, P: 2085-2098
MicroRNAs differentially present in the plasma of HIV elite controllers reduce HIV infection in vitro

Rita Reynoso
Natalia Laufer
Johannes Grillari
ResearchOpen Access01 Aug 2014
Scientific Reports

Volume: 4, P: 1-9
Global Roadkill Data: a dataset on terrestrial vertebrate mortality caused by collision with vehicles

Clara Grilo
Tomé Neves
Eric Guinard
ResearchOpen Access31 Mar 2025
Scientific Data

Volume: 12, P: 1-14