Nature Search

The role of low-complexity repeats in RNA–RNA interactions and a deep learning framework for duplex prediction

Interactions between long RNA molecules play essential roles in shaping gene regulation. Here, the authors show that low-complexity repeats drive stable contacts between RNAs and present RIME, a deep learning model that improves the prediction of these interactions using sequence information.

Adriano Setti
Giorgio Bini
Gian Gaetano Tartaglia
ResearchOpen Access23 Jan 2026
Nature Communications

P: 1-28
A multi-joint soft exosuit improves shoulder and elbow motor functions in individuals with spinal cord injury

A lightweight, modular assistive soft exosuit is introduced, which supports shoulder and elbow movement in individuals with cervical spinal cord injury. The device enhances endurance and range of motion, reduces muscle effort and improves clinical test scores.

Roberto Ferroni
Gaetano D’Avola
Tommaso Proietti
Research22 Sept 2025
Nature Machine Intelligence

Volume: 7, P: 1390-1402
RNA sequestration in P-bodies sustains myeloid leukaemia

Kodali, Proietti et al. report that increased numbers of P-bodies in leukaemia cells account for sequestration and prevention of tumour-suppressive mRNAs from being translated, which could be targeted as a potential intervention in myeloid leukaemia.

Srikanth Kodali
Ludovica Proietti
Bruno Di Stefano
Research21 Aug 2024
Nature Cell Biology

Volume: 26, P: 1745-1758
Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction

Combining human proteome and transcriptome analyses and Mendelian randomization on a large genetic dataset of HFpEF and HFrEF cases, Rasooly et al. identified 58 potential therapeutic targets specific for either HEpEF or HFrEF and created their therapeutic target profiles.

Danielle Rasooly
Claudia Giambartolomei
Jacob Joseph
Research06 Feb 2025
Nature Cardiovascular Research

Volume: 4, P: 293-311
Physical activity decreases the risk of cancer reclassification in patients on active surveillance: a multicenter retrospective study

Aldo Brassetti
Mariaconsiglia Ferriero
Giuseppe Simone
Research18 May 2021
Prostate Cancer and Prostatic Diseases

Volume: 24, P: 1151-1157
ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens

The generation of protective secretory IgA is a desired outcome of oral vaccination. Here, the authors show that the depletion of intestinal ATP significantly improves the production and response of high-affinity IgA against both live and inactivated oral vaccines.

Michele Proietti
Lisa Perruzza
Fabio Grassi
ResearchOpen Access16 Jan 2019
Nature Communications

Volume: 10, P: 1-11
3D vertical nanostructures for enhanced infrared plasmonics

Mario Malerba
Alessandro Alabastri
Francesco De Angelis
ResearchOpen Access10 Nov 2015
Scientific Reports

Volume: 5, P: 1-8
High-performance and site-directed in utero electroporation by a triple-electrode probe

In uteroelectroporation allows the labelling of specific populations of neurons in the developing mouse brain. The authors of this paper present a simple modification of this method that increases labelling efficiency and allows, for the first time, transfection of Purkinje cells in the rat cerebellum.

Marco dal Maschio
Diego Ghezzi
Laura Cancedda
ResearchOpen Access17 Jul 2012
Nature Communications

Volume: 3, P: 1-11
Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML

Elizabeth Heyes
Luisa Schmidt
Florian Grebien
Research23 Feb 2021
Leukemia

Volume: 35, P: 2526-2538
Prophylactic heparin and risk of orotracheal intubation or death in patients with mild or moderate COVID-19 pneumonia

Alessandra Vergori
Patrizia Lorenzini
Sara Zito
ResearchOpen Access31 May 2021
Scientific Reports

Volume: 11, P: 1-10

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The role of low-complexity repeats in RNA–RNA interactions and a deep learning framework for duplex prediction

A multi-joint soft exosuit improves shoulder and elbow motor functions in individuals with spinal cord injury

RNA sequestration in P-bodies sustains myeloid leukaemia

Large-scale multi-omics identifies drug targets for heart failure with reduced and preserved ejection fraction

Physical activity decreases the risk of cancer reclassification in patients on active surveillance: a multicenter retrospective study

ATP released by intestinal bacteria limits the generation of protective IgA against enteropathogens

3D vertical nanostructures for enhanced infrared plasmonics

High-performance and site-directed in utero electroporation by a triple-electrode probe

Identification of gene targets of mutant C/EBPα reveals a critical role for MSI2 in CEBPA-mutated AML

Prophylactic heparin and risk of orotracheal intubation or death in patients with mild or moderate COVID-19 pneumonia

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