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Scientific Reports (2)
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Advanced filters: Author: Gaili Ji Clear advanced filters

MLKL PARylation in the endothelial niche triggers angiocrine necroptosis to evade cancer immunosurveillance and chemotherapy

Yang, Li, Huang, Ji, Luo, Jiang and colleagues report that chemotherapy induces MLKL PARylation and necroptosis in tumour endothelial cells, which in turn affects tumour-associated macrophages and CD8⁺ T cells, promoting immunosuppression and tumorigenesis.

Nan Yang
Xiaoxue Li
Zhongwei Cao
Research05 Sept 2025
Nature Cell Biology

Volume: 27, P: 1526-1542
Endothelial Cords Promote Tumor Initial Growth prior to Vascular Function through a Paracrine Mechanism

Chengjian Zhao
Wei Zhang
Hanshuo Yang
ResearchOpen Access14 Jan 2016
Scientific Reports

Volume: 6, P: 1-13
Mitochondrial C11orf83 is a potent Antiviral Protein Independent of interferon production

Yun Yang
Shaoquan Xiong
Hanshuo Yang
ResearchOpen Access18 Apr 2017
Scientific Reports

Volume: 7, P: 1-11