Long non-coding RNA (lncRNA) has diverse functions. Here the authors show that a lncRNA, NORAD, interacts with an immune transcription factor, STAT3, to facilitate STAT3 nuclear import and thereby modulating the intranuclear balance between STAT3 and STAT1 and the downstream activation of anti-viral immunity in vitro.
- Amir Argoetti
- Dor Shalev
- Yael Mandel-Gutfreund
