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Molecular Psychiatry (1)

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Showing 1–3 of 3 results

Advanced filters: Author: Gavin C. Touponse Clear advanced filters

Cholinergic modulation of dopamine release drives effortful behaviour

In the nucleus accumbens, acetylcholine boosts dopamine release to promote effortful behaviour.

Gavin C. Touponse
Matthew B. Pomrenze
Neir Eshel
ResearchOpen Access28 Jan 2026
Nature

P: 1-10
Opponent control of reinforcement by striatal dopamine and serotonin

A double-transgenic mouse model that enables monitoring or manipulation of dopamine and serotonin simultaneously in the brain’s nucleus accumbens shows that these neuromodulators have opponent roles in reward learning.

Daniel F. Cardozo Pinto
Matthew B. Pomrenze
Robert C. Malenka
Research25 Nov 2024
Nature

Volume: 639, P: 143-152
5-HT_2C receptors in the nucleus accumbens constrain the rewarding effects of MDMA

Matthew B. Pomrenze
Sam Vaillancourt
Boris D. Heifets
ResearchOpen Access24 Jul 2025
Molecular Psychiatry

Volume: 30, P: 5405-5416