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Advanced filters: Author: Genzui Setsu Clear advanced filters

Gpr176 is a Gz-linked orphan G-protein-coupled receptor that sets the pace of circadian behaviour

The suprachiasmatic nucleus (SCN) is the central regulator of circadian rhythms. Here the authors identify mouse Gpr176 as a pace modulator of this circadian clock and characterize its mode of action as coupling to Gz rather than Gi subunits.

Masao Doi
Iori Murai
Hitoshi Okamura
ResearchOpen Access17 Feb 2016
Nature Communications

Volume: 7, P: 1-13
Gpr19 is a circadian clock-controlled orphan GPCR with a role in modulating free-running period and light resetting capacity of the circadian clock

Yoshiaki Yamaguchi
Iori Murai
Masao Doi
ResearchOpen Access17 Nov 2021
Scientific Reports

Volume: 11, P: 1-13
Identification and functional characterisation of N-linked glycosylation of the orphan G protein-coupled receptor Gpr176

Tianyu Wang
Shumpei Nakagawa
Masao Doi
ResearchOpen Access10 Mar 2020
Scientific Reports

Volume: 10, P: 1-12