Nature Search

Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study

Estimates from the Global Burden of Disease study reveal declines in chronic respiratory disease mortality between 1990 and 2023—especially during the COVID-19 pandemic—but the burdens on people affected remain substantial.

Jiyeon Oh
Soeun Kim
Dong Keon Yon
Research06 Jan 2026
Nature Medicine

Volume: 32, P: 197-223
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

Systematic analysis from the Global Burden of Disease study reported that, despite global improvements from 1990 to 2021, dietary iron deficiency-associated disease burden remains high in women, children and residents in low socio-demographic index countries.

Sooji Lee
Yejun Son
Nicholas. J. Kassebaum
Research22 Apr 2025
Nature Medicine

Volume: 31, P: 1809-1829
A temperate Earth-sized planet with tidal heating transiting an M6 star

The authors report on a temperate Earth-sized planet orbiting the cool M6 dwarf LP 791-18 with a radius of 1.03 ± 0.04 R_⊕ and an equilibrium temperature of 300–400 K, with the permanent night side plausibly allowing for water condensation.

Merrin S. Peterson
Björn Benneke
Thomas Barclay
Research17 May 2023
Nature

Volume: 617, P: 701-705
Adenovirus E1A products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters

Keith A. Webster
George E. O. Muscat
Larry Kedes
Research07 Apr 1988
Nature

Volume: 332, P: 553-557
Neurobiological Similarities in Depression and Drug Dependence: A Self-Medication Hypothesis

Athina Markou
Thomas R Kosten
George F Koob
Reviews01 Mar 1998
Neuropsychopharmacology

Volume: 18, P: 135-174
Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000–2018

Bhattacharjee and Schaeffer et al. map exclusive breastfeeding (EBF) in 94 low- and middle-income countries (LMICs), finding increased EBF practice and reduced subnational variation across the majority of LMICs from 2000 to 2018. However, only six LMICs will meet WHO’s target of ≥70% EBF by 2030 nationally, and only three will achieve this in all districts.

Natalia V. Bhattacharjee
Lauren E. Schaeffer
Simon I. Hay
ResearchOpen Access03 Jun 2021
Nature Human Behaviour

Volume: 5, P: 1027-1045
The overlapping burden of the three leading causes of disability and death in sub-Saharan African children

In this disease mapping study, the authors estimate disability-adjusted life year rates for three of the major causes of mortality for children under five 43 countries in sub-Saharan Africa. They identify significant heterogeneity at the subnational level, highlighting the need for a targeted intervention approach.

Robert C. Reiner Jr.
Catherine A. Welgan
Simon I. Hay
ResearchOpen Access06 Dec 2022
Nature Communications

Volume: 13, P: 1-14
Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

Analysis of HbA1c and FPG levels across 117 population-based studies demonstrates regional variation in prevalence of previously undiagnosed screen-detected diabetes using one or both measures and suggests that use of elevated FPG alone could underestimate diabetes prevalence in low- and middle-income countries.

Bin Zhou
Kate E. Sheffer
Majid Ezzati
ResearchOpen Access09 Nov 2023
Nature Medicine

Volume: 29, P: 2885-2901
A multinational Delphi consensus to end the COVID-19 public health threat

A diverse, multidisciplinary panel of 386 experts in COVID-19 response from 112 countries provides health and social policy actions to address inadequacies in the pandemic response and help to bring this public health threat to an end.

Jeffrey V. Lazarus
Diana Romero
Anne Øvrehus
ResearchOpen Access03 Nov 2022
Nature

Volume: 611, P: 332-345
Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Heart rate variability (HRV) describes the individual variation in cardiac cycle duration and is a measure of vagal control of heart rate. Here, the authors identify seventeen single-nucleotide polymorphisms associated with HRV, lending new insight into the vagal regulation of heart rhythm.

Ilja M. Nolte
M. Loretto Munoz
Eco J. C. de Geus
ResearchOpen Access14 Jun 2017
Nature Communications

Volume: 8, P: 1-17
Ancient human genomes suggest three ancestral populations for present-day Europeans

A sequencing study comparing ancient and contemporary genomes reveals that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, ancient north Eurasians (related to Upper Palaeolithic Siberians) and early European farmers of mainly Near Eastern origin.

Iosif Lazaridis
Nick Patterson
Johannes Krause
Research17 Sept 2014
Nature

Volume: 513, P: 409-413
Sox18 Is Transiently Expressed during Angiogenesis in Granulation Tissue of Skin Wounds with an Identical Expression Pattern to Flk-1 mRNA

Ian A Darby
Teresa Bisucci
Peter Koopman
Research01 Jul 2001
Laboratory Investigation

Volume: 81, P: 937-943
Not a minute to waste

We are finally beginning to unlock the mechanisms underlying Ca²⁺-stimulated muscle differentiation and cytokine-mediated muscle wasting. Gaining a better understanding of the signaling pathways that regulate muscle development and decay improves the prospects for repairing aged, injured and diseased muscle.

George E.O. Muscat
Uwe Dressel
News & Views01 Nov 2000
Nature Medicine

Volume: 6, P: 1216-1217
Advancing the global public health agenda for NAFLD: a consensus statement

Non-alcoholic fatty liver disease (NAFLD) is a potentially serious liver disease with a substantial burden worldwide. In this Consensus Statement, a global multidisciplinary group of experts develop consensus statements and recommendations addressing a broad range of topics on NAFLD to raise awareness and spur action.

Jeffrey V. Lazarus
Henry E. Mark
Ming-Hua Zheng
Reviews27 Oct 2021
Nature Reviews Gastroenterology & Hepatology

Volume: 19, P: 60-78
Observation of the rare B_s⁰ →µ⁺µ⁻ decay from the combined analysis of CMS and LHCb data

Combined analysis of proton-proton collision data from the Large Hadron Collider at CERN by the CMS and LHCb collaborations leads to the observation of the extremely rare decay of the strange B meson into muons; the result is compatible with the standard model of particle physics, and does not show any signs of new physics, such as supersymmetry.

V. Khachatryan
A.M. Sirunyan
E. Pesen
ResearchOpen Access13 May 2015
Nature

Volume: 522, P: 68-72
Sox18 induces development of the lymphatic vasculature in mice

A role for Sox18 transcription factor has been suggested by lymphatic dysfunction in the human syndrome hypotrichosis-lymphedema-telangiectasia (HLT), which is caused by mutations in Sox18. This paper shows that Sox18 directly activates Prox1 transcription. Sox18-null embryos show a complete absence of Prox1-positive lymphatic endothelial cells emanating from the cardinal vein.

Mathias François
Andrea Caprini
Peter Koopman
Research01 Dec 2008
Nature

Volume: 456, P: 643-647
A giant planet undergoing extreme-ultraviolet irradiation by its hot massive-star host

The giant planet KELT-9b has a dayside temperature of about 4,600 K, which is sufficiently high to dissociate molecules and to evaporate its atmosphere, owing to its hot stellar host.

B. Scott Gaudi
Keivan G. Stassun
Patricia Trueblood
Research05 Jun 2017
Nature

Volume: 546, P: 514-518
Narrowing the gap for hematopoietic stem cell transplantation in the East-Mediterranean/African region: comparison with global HSCT indications and trends

Helen Baldomero
Mahmoud Aljurf
Nicolas Novitzky
Research06 Aug 2018
Bone Marrow Transplantation

Volume: 54, P: 402-417
Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020

Julie-Anne Little
Nathan G. Congdon
Rupert Bourne
ResearchOpen Access04 Jul 2024
Eye

Volume: 38, P: 2083-2101
Global estimates on the number of people blind or visually impaired by glaucoma: A meta-analysis from 2000 to 2020

Rupert R. A. Bourne
Jost B. Jonas
Jaimie D. Steinmetz
ResearchOpen Access02 Apr 2024
Eye

Volume: 38, P: 2036-2046

Search

Global, regional, and national burden of chronic respiratory diseases and impact of the COVID-19 pandemic, 1990–2023: a Global Burden of Disease study

Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Global, regional and national burden of dietary iron deficiency from 1990 to 2021: a Global Burden of Disease study

A temperate Earth-sized planet with tidal heating transiting an M6 star

Adenovirus E1A products suppress myogenic differentiation and inhibit transcription from muscle-specific promoters

Neurobiological Similarities in Depression and Drug Dependence: A Self-Medication Hypothesis

Mapping inequalities in exclusive breastfeeding in low- and middle-income countries, 2000–2018

The overlapping burden of the three leading causes of disability and death in sub-Saharan African children

Global variation in diabetes diagnosis and prevalence based on fasting glucose and hemoglobin A1c

A multinational Delphi consensus to end the COVID-19 public health threat

Genetic loci associated with heart rate variability and their effects on cardiac disease risk

Ancient human genomes suggest three ancestral populations for present-day Europeans

Sox18 Is Transiently Expressed during Angiogenesis in Granulation Tissue of Skin Wounds with an Identical Expression Pattern to Flk-1 mRNA

Not a minute to waste

Advancing the global public health agenda for NAFLD: a consensus statement

Observation of the rare B_s⁰ →µ⁺µ⁻ decay from the combined analysis of CMS and LHCb data

Sox18 induces development of the lymphatic vasculature in mice

A giant planet undergoing extreme-ultraviolet irradiation by its hot massive-star host

Narrowing the gap for hematopoietic stem cell transplantation in the East-Mediterranean/African region: comparison with global HSCT indications and trends

Global estimates on the number of people blind or visually impaired by Uncorrected Refractive Error: a meta-analysis from 2000 to 2020

Global estimates on the number of people blind or visually impaired by glaucoma: A meta-analysis from 2000 to 2020

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