Multiple sclerosis (MS) is generally considered to be an autoimmune, inflammatory disease. In this provocative Perspective, Stys and colleagues propose that non-inflammatory, primary progressive MS is the 'real' MS, and that inflammatory forms of the disorder reflect an aberrant immune reaction to ongoing cytodegeneration.
- Peter K. Stys
- Gerald W. Zamponi
- Jeroen J. G. Geurts
