The presence of anti-citrullinated protein antibodies (ACPAs) is a useful biomarker in rheumatoid arthritis (RA). New technological advances are helping to unravel the role of the anti-citrullinated antigen response in RA pathogenesis, in particular, the contribution of ACPAs, ACPA glycosylation and ACPA-expressing B cells.
- Hans Ulrich Scherer
- Tom W. J. Huizinga
- Rene E. M. Toes