Mutations in the centrosome-cilia gene, Cc2d2a, result in Meckel and Joubert syndromes in humans. By creating Cc2d2a-mutant mice, Veleri et al.show that this gene encodes a component of subdistal appendages; ciliary structures thought to be required to anchor cilia to the microtubule network.
- Shobi Veleri
- Souparnika H. Manjunath
- Anand Swaroop
