The incidence of obesity, a potential risk factor for prostate disease, is rising sharply in the western world, as is the incidence of prostate tumors. In this extended Viewpoint, Kulkarni and Getzenberg propose that the relationship between obesity and prostate disease might be mediated by the autotaxin–lysophosphatidic acid (ATX–LPA) axis.
- Prakash Kulkarni
- Robert H Getzenberg