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Efficient and accurate constant potential simulation is essential for electrochemical modeling. Here, authors propose a constant potential framework by combining the machine learning force field with the charge equilibration method to study the dendrites nucleation at the Li metal battery interface.

This study reveals how tomato plants recruit specific bacteria to combat Fusarium wilt. A key bacterium is identified to thrive on root-derived compounds and suppress the fungal pathogen, offering insights into plant-microbe defense alliances.

North Atlantic waters have been aging over the past three decades, indicating a slowdown in ocean ventilation. By combining observations with models, this slowdown is likely driven by climate change.

Iron pnictide superconductors represent a suggestive alternative to cuprate superconductors for achieving high transition temperatures. Using in situ angle-resolved photoemission spectroscopy, the electronic properties of FeSe are examined as a function of film thickness, providing valuable insights into the mechanism driving the superconductivity in this material.

Disruption of dendritic cell (DC) interstitial motility in the tumour microenvironment promotes immune evasion, and enhancement of DC interstitial motility offers a route for DC-centric immunotherapy.

Fang and colleagues revealed cryo-electron microscopy structures of human THIK1, identifying two inner gates and a C-type selectivity filter gate, distinct from other two-pore-domain potassium channels. Their findings uncover the channel gating mechanism, offering insights for developing THIK1-targeted neurotherapeutics.

The authors provide insights into the role of neuronal CCL2 expression, which is triggered with hyperglycaemia and modulates anxiety disorders under conditions of diabetes.

Hydroxyl radicals (OH) determine the tropospheric self-cleansing capacity. This study reveals that reactive aldehyde chemistry plays an important role in OH formation and helps narrow the gap between ambient OH observations and model simulations.

An enhanced superconducting pairing temperature (T_g) has only been observed in single-layer FeSe interfaced with TiO_x system. Here, the authors construct a new interface composed of single-layer FeSe interfaced with LaFeO₃ showing a highest T_g of 80 K among all-known interfacial superconductors.

Brown planthopper is a rice-specific piercing-sucking pest. This study reveals that ACL1-ROC4/5 complexes regulate both brown planthopper resistance and drought tolerance in rice through modulating bulliform cell development and cuticular wax content.

The authors improve the energy storage performance and high temperature stability of lead-free tetragonal tungsten bronze dielectric ceramics through high entropy strategy and band gap engineering.

Synthesis of aryl phosphorus compounds with electron-withdrawing substituents on the arene is difficult to do simply. Here the authors show a method to form aryl carbon-phosphorus bonds through electrochemistry, without requiring any catalyst or external oxidant.

Analyses of atmospheric nitrogen chemistry in Beijing’s air pollution during the COVID-19 lockdown suggest an increasing role of nighttime nitrogen chemistry in haze formation above the city.

A high-quality reference genome assembly of cauliflower C-8 (V2) and genomic analyses of 971 diverse accessions and their relatives reveal the stepwise domestication and the genetic mechanism of curd biogenesis.

Here, the authors introduce Photoacoustic Tomography with Temporal Encoding Reconstruction (PATTERN) - a high-speed, non-destructive photoacoustic brain imaging technique that constructs 3D fluorescent maps of the brain and improves upon some of the limitations associated with traditional whole-brain optical imaging techniques.

ATM signaling is known to be activated following DNA double-strand breaks. Here, this study provides evidences that ATM-dependent signaling pathway is activated by DNA single-strand breaks and regulated by its direct activator protein APE1.

The plant commensal Bacillus velezensis SQR9 uses its type VII secretion system to deliver effector protein YukE to plant roots, which causes iron leakage and promotes its colonization on roots.

Multiple parameters are generally responsible for the reactivity of particulate catalysts, although nanoparticle proximity is often neglected. Here the authors report the impact of such structural factor using the hydrogenation of benzaldehyde over PdAu nanoparticles supported on macroporous SiO₂ as the probe reaction.

Bio-oil is a potential major source of renewable fuels and chemicals. Here, the authors report a palladium-molybdenum mixed catalyst for the selective hydrodeoxygenation of water-insoluble bio-oil to mixtures of alkanes with high carbon yield.

The authors find that, in a high-fat diet (HFD) mouse model, levels of Stella protein are reduced in oocytes, leading to abnormal epigenetic patterning during development and to embryonic growth defects. Overexpression of Stella in oocytes from HFD-fed mice partially ameliorates developmental defects.

Cellular stress results in the release of damage-associated molecular pattern (DAMP) molecules that promote inflammatory responses. Here Ping Wang and colleagues show that cold-inducible RNA-binding protein (CIRP) is a DAMP that is released into the circulation in response to hemorrhagic shock and sepsis. It promotes proinflammatory cytokine release by binding to the TLR4-MD2 complex. Blockade of CIRP reduces inflammation, organ injury and mortality in animal models of hemorrhage and sepsis, suggesting that CIRP may be targeted therapeutically in these conditions.

Asymmetric synthetic photoelectrochemical transformations are underdeveloped. Now, the combination of a photocatalyst, a chiral copper catalyst and an electrode allows the enantioselective cyanation of benzylic C–H bonds without a chemical oxidant.

Double-stranded RNA-dependent protein kinase (PKR) is shown to be a key regulator of the inflammasome; PKR is central for caspase-1 activation and the release of interleukin (IL)-1β, IL-18 and high-mobility group box 1 (HMGB1) in response to a diverse range of stimuli.

Yuda et al. report the development and evaluation of a novel selective MCL-1 inhibitor, ABBV-467. The compound is efficacious in preclinical models but increases in cardiac troponin are seen in a first-in-human study, suggesting potential cardiac toxicity of the drug.

In the quest for more efficient and sustainable asymmetric catalytic methods, synthetic organic chemistry has relentlessly explored innovative techniques. This Comment highlights an emerging topic — photoelectrochemical asymmetric catalysis (PEAC) — which fuses molecular photoelectrocatalysis with asymmetric catalysis.