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Showing 1–8 of 8 results

Advanced filters: Author: Halil Aydin Clear advanced filters

Molecular architecture of the human sperm IZUMO1 and egg JUNO fertilization complex

This study describes the structures of the IZUMO1 protein, found on sperm, and the JUNO protein, found on eggs, and sheds light on their roles in sperm–egg fusion during fertilization.

Halil Aydin
Azmiri Sultana
Jeffrey E. Lee
Research15 Jun 2016
Nature

Volume: 534, P: 562-565
Cardiolipin dynamics promote membrane remodeling by mitochondrial OPA1

This study reveals how cardiolipin governs mitochondrial morphology by modulating the activity of human OPA1 and how its replacement by monolyso-cardiolipin, as observed in Barth syndrome, impacts mitochondrial membrane-shaping mechanisms.

Sirikrishna Thatavarthy
Luciano A. Abriata
Halil Aydin
ResearchOpen Access30 Sept 2025
Nature Communications

Volume: 16, P: 1-18
Structural mechanism of mitochondrial membrane remodelling by human OPA1

Human OPA1 embeds itself into cardiolipin-containing membranes through a lipid-binding paddle domain, and OPA1 oligomerization through multiple assembly interfaces promotes the helical assembly of a flexible OPA1 lattice on the membrane, driving mitochondrial fusion in cells.

Alexander von der Malsburg
Gracie M. Sapp
Halil Aydin
Research23 Aug 2023
Nature

Volume: 620, P: 1101-1108
Weight loss dynamics after laparoscopic sleeve gastrectomy: a retrospective single center analysis with age and preoperative weight stratification

Burak Kankaya
Suleyman Buyukasik
Halil Alis
ResearchOpen Access13 Mar 2025
Scientific Reports

Volume: 15, P: 1-11
Fatty acyl-coenzyme A activates mitochondrial division through oligomerization of MiD49 and MiD51

Liu et al. find that long-chain acyl-coenzyme A activates two mitochondrial fission proteins, MiD49 and MiD51, by inducing their oligomerization. This activates their ability to stimulate DRP1 GTPase activity and triggers mitochondrial division.

Ao Liu
Frieda Kage
Henry N. Higgs
Research09 Apr 2024
Nature Cell Biology

Volume: 26, P: 731-744
Synthesis of Conductive Carbon Aerogels Decorated with β-Tricalcium Phosphate Nanocrystallites

Atakan Tevlek
Abdulraheem M. N. Atya
Halil M. Aydin
ResearchOpen Access01 Apr 2020
Scientific Reports

Volume: 10, P: 1-10
Drug-resistant Staphylococcus aureus bacteria detection by combining surface-enhanced Raman spectroscopy (SERS) and deep learning techniques

Fatma Uysal Ciloglu
Abdullah Caliskan
Omer Aydin
ResearchOpen Access16 Sept 2021
Scientific Reports

Volume: 11, P: 1-12
Optimal use of oral nutritional supplements (ONS) in medical nutrition therapy: ONS consensus report from KEPAN

Gulistan Bahat
Muge Akmansu
Birgul Dag
Reviews09 Nov 2022
European Journal of Clinical Nutrition

Volume: 77, P: 705-709