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Showing 1–7 of 7 results

Advanced filters: Author: Haoliang Xue Clear advanced filters

Optineurin-facilitated axonal mitochondria delivery promotes neuroprotection and axon regeneration

Optineurin is linked to ALS and glaucoma, but the mechanism is unknown. Here, the authors show that optineurin mutation causes deficits in axonal mitochondria transport and neurodegeneration, enhancing of which achieves axon protection and regeneration.

Dong Liu
Hannah C. Webber
Yang Hu
ResearchOpen Access20 Feb 2025
Nature Communications

Volume: 16, P: 1-23
Single-cell and spatial transcriptomics analysis of non-small cell lung cancer

Myeloid cell populations play a critical role in lung cancer progression. Here, the authors use scRNA-seq and spatial transcriptomics to identify changes in the phenotype of macrophages within the tumour microenvironment.

Marco De Zuani
Haoliang Xue
Ana Cvejic
ResearchOpen Access23 May 2024
Nature Communications

Volume: 15, P: 1-17
Comparison of the effect on bone healing process of different implants used in minimally invasive plate osteosynthesis: limited contact dynamic compression plate versus locking compression plate

Zichao Xue
Haitao Xu
Zhiquan An
ResearchOpen Access25 Nov 2016
Scientific Reports

Volume: 6, P: 1-9
Ambient-pressure superconductivity onset above 40 K in (La,Pr)₃Ni₂O₇ films

Ambient-pressure superconductivity onset above the McMillan limit in bilayer nickelate epitaxial thin films is reported, paving the way for comprehensive investigations of superconductors and for exploring superconductivity at higher transition temperatures in heterostructures.

Guangdi Zhou
Wei Lv
Zhuoyu Chen
Research17 Feb 2025
Nature

Volume: 640, P: 641-646
Single-cell multi-omics map of human fetal blood in Down syndrome

Using single-cell and multi-omics data of fetal blood, a high-resolution molecular map of dysregulated haematopoiesis in Down syndrome is provided.

Andrew R. Marderstein
Marco De Zuani
Ana Cvejic
ResearchOpen Access25 Sept 2024
Nature

Volume: 634, P: 104-112
Maprotiline restores ER homeostasis and rescues neurodegeneration via Histamine Receptor H1 inhibition in retinal ganglion cells

ER stress is associated with various neurodegenerative diseases. This study found that FDA approved drug, maprotiline, inhibits histamine receptor H1-mediated ER stress and provides significant neuroprotection in mouse glaucoma model.

Wei Chen
Pingting Liu
Yang Hu
ResearchOpen Access10 Nov 2022
Nature Communications

Volume: 13, P: 1-18
Potato growth, photosynthesis, yield, and quality response to regulated deficit drip irrigation under film mulching in a cold and arid environment

Fuqiang Li
Haoliang Deng
Hengjia Zhang
ResearchOpen Access05 Aug 2021
Scientific Reports

Volume: 11, P: 1-16