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Pathology and viral evolutionary dynamics in a hamster model of persistent SARS-CoV-2 infection

SARS-CoV-2 persistence in IL2rg-deficient hamsters shows sustained replication, tissue dissemination, and dynamic intra-host evolution, establishing a model to define mechanisms driving long-term infection and its effects.

Wanting Wei
Makoto Kuroda
Peter J. Halfmann
ResearchOpen Access08 Jan 2026
Communications Biology

P: 1-11

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