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Advanced filters: Author: Hengrong Jiang Clear advanced filters

A programmable pAgo nuclease with high activity and specificity for efficient DNA and RNA manipulation

GgeAgo protein from a thermophilic organism utilizes 5’ phosphorylated DNA guides to cleave both ssDNA, dsDNA and RNA, which have been employed in developing an effective DNA and RNA manipulation tool in DNA cloning and nucleic acid detection

Jiao Hu
Yangyang Hu
Lixin Ma
ResearchOpen Access26 Nov 2025
Communications Biology

Volume: 8, P: 1-11

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A programmable pAgo nuclease with high activity and specificity for efficient DNA and RNA manipulation

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