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Showing 1–3 of 3 results

Advanced filters: Author: Hongxuan Cao Clear advanced filters

Inhibiting Mrt4-rRNA interaction with fumaramidmycin-based derivatives as an antifungal strategy

Drug resistance and limited antifungal therapies necessitate innovative strategies. Using cis-fumaramidmycin-derived probes, the authors reveal inhibition of the Mrt4- rRNA interaction as a promising vulnerability for combating drug resistant fungi.

Hongxuan Cao
Jie Tu
Yanliang Ren
ResearchOpen Access04 Mar 2026
Nature Communications

Volume: 17, P: 1-18
Pleistocene terrestrial warming trend in East Asia linked to Antarctic ice sheets growth

The authors quantify terrestrial temperature evolution over the past 2 million years by fossil lipids preserved in an ancient lake in East Asia. They showed a long-term warming trend that diverges from the contemporaneous global sea surface cooling.

Huanye Wang
Weiguo Liu
Zhisheng An
ResearchOpen Access10 Sept 2025
Nature Communications

Volume: 16, P: 1-9
Oxygenated deep waters fed early Atlantic overturning circulation upon Antarctic glaciation

Deep-ocean oxygenation patterns consistent with an active Atlantic meridional overturning circulation emerged following the Eocene-Oligocene transition about 34 million years ago, according to biomarker records from the northwest North Atlantic.

Huanye Wang
Weiguo Liu
Zhonghui Liu
Research16 Oct 2023
Nature Geoscience

Volume: 16, P: 1014-1019