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Advanced filters: Author: Hsin-En Wu Clear advanced filters

ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression

Hsu, Wang, Manne et al. identify ALDH4A1 as a component of the mitochondrial pyruvate carrier complex, which plays a non-canonical role in regulating pyruvate homeostasis in mitochondria, TCA cycle entry and tumour suppression.

Che-Chia Hsu
Chi-Yun Wang
Hui-Kuan Lin
Research12 May 2025
Nature Cell Biology

Volume: 27, P: 847-862
No association between alcohol consumption and pancreatic cancer even among individuals genetically susceptible to the carcinogenicity of alcohol

Yan-Shen Shan
Li-Tzong Chen
Jeffrey S. Chang
ResearchOpen Access15 Jul 2021
Scientific Reports

Volume: 11, P: 1-9

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ALDH4A1 functions as an active component of the MPC complex maintaining mitochondrial pyruvate import for TCA cycle entry and tumour suppression

No association between alcohol consumption and pancreatic cancer even among individuals genetically susceptible to the carcinogenicity of alcohol

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