Antibody-dependent enhancement (ADE) is an important safety concern for vaccine development against dengue virus (DENV) and the antigenically related Zika virus (ZIKV). Gao and colleagues designed a ZIKV vaccine that induced sterilizing immunity and fetal protection in mice challenged with ZIKV and did not induce ADE following subsequent DENV infection.
- Lianpan Dai
- Kun Xu
- George F. Gao
