Mona Shehata et al. study the effects of metformin, an antidiabetic drug with potential as a breast cancer treatment, in the normal mouse mammary gland. They find that metformin targets hormone receptor positive (HR+) luminal cells and decreases the progenitor capacity of these cells when administered at clinically relevant doses.
- Mona Shehata
- Hyeyeon Kim
- Rama Khokha
