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Showing 1–2 of 2 results
Advanced filters: Author: Indrawan J. McAlpine Clear advanced filters
  • The ambiphilic reactivity of alkyl sulfonyl fluorides in stereoselective cyclopropanation under Pd(II) catalysis is reported. The method provides convenient access to cis-disubstituted cyclopropanes that are otherwise challenging to access. A representative carboxylic acid cyclopropane building block is scaled up to 100 mmol, demonstrating the practicality of this transformation.

    • Yilin Cao
    • Warabhorn Rodphon
    • Keary M. Engle
    ResearchOpen Access
    Nature Synthesis
    P: 1-9
  • Dihydrobenzofurans and indolines are common substructures in medicines and natural products. Herein, the authors report a palladium-catalyzed [3 + 2] (hetero)annulation proceeding in an anti-selective fashion and enabling direct access to these valuable heterocycles with broad reaction scope.

    • Hui-Qi Ni
    • Ilia Kevlishvili
    • Keary M. Engle
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-8