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Showing 1–15 of 15 results
Advanced filters: Author: Ivano Bertini Clear advanced filters

  • Studying many-body quantum chaos on current quantum hardware is hindered by noise and limited scalability. Now it is shown that a superconducting processor, combined with error mitigation, can accurately simulate dual-unitary circuit dynamics.

    • Laurin E. Fischer
    • Matea Leahy
    • Sergey N. Filippov
    Research
    Nature Physics
    P: 1-6

  • Unpaired electrons can exert effects that allow interatomic contacts in molecules to be detected more easily using nuclear magnetic resonance. One such effect reveals unusual interactions between certain atoms in a protein.

    • Ivano Bertini
    • Claudio Luchinat
    News & Views
    Nature
    Volume: 470, P: 469-470

    • Luciano A Abriata
    • Lucia Banci
    • Shenlin Wang
    Research
    Nature Chemical Biology
    Volume: 4, P: 599-601

  • Analysis of proteins within their native environment can confirm and extend in vitro–derived conclusions. NMR analysis of superoxide dismutase 1 in live human cells now corroborates previously identified steps on the maturation pathway and demonstrates copper-independent function of the chaperone CCS.

    • Lucia Banci
    • Letizia Barbieri
    • A Radu Aricescu
    Research
    Nature Chemical Biology
    Volume: 9, P: 297-299

  • Images collected during NASA’s DART mission of the asteroid Didymos and its moon, Dimorphos, are used to explore the origin and evolution of the binary system. Authors analysis indicate that both asteroids are weak rubble piles and that Didymos’ surface should be about 40 to 130 times older than Dimorphos.

    • Olivier Barnouin
    • Ronald-Louis Ballouz
    • Andrew S. Rivkin
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14

  • In the past decade, the ability of nuclear magnetic resonance (NMR) spectroscopy to provide information on intermolecular interactions that is valuable in drug discovery has been increasingly appreciated. Pellecchia and colleagues provide their collective evaluation of the major applications of NMR in drug discovery, focusing on hit and lead generation, and critically analyse its current and potential utility.

    • Maurizio Pellecchia
    • Ivano Bertini
    • Gregg Siegal
    Reviews
    Nature Reviews Drug Discovery
    Volume: 7, P: 738-745

  • The authors report on a determination of the momentum transferred to an asteroid by kinetic impact, showing that the DART kinetic impact was highly effective in deflecting the asteroid Dimorphos.

    • Andrew F. Cheng
    • Harrison F. Agrusa
    • Giovanni Zanotti
    ResearchOpen Access
    Nature
    Volume: 616, P: 457-460

  • MIA40, found in the mitochondrial intermembrane space, is a central component in the import system that transports certain cysteine motif–containing proteins into the mitochondria. New analyses reveal that MIA40 forms a novel thioredoxin fold. Its redox center catalyzes the formation of the first disulfide bond of a substrate, causing the susbtrate's second disulfide to require only oxygen for its formation.

    • Lucia Banci
    • Ivano Bertini
    • Kostas Tokatlidis
    Research
    Nature Structural & Molecular Biology
    Volume: 16, P: 198-206

  • The ‘onion-like’ stratification of the two lobes of the comet 67P/Churyumov–Gerasimenko reveals that its unusual shape is the result of a gentle collision merging two kilometre-sized objects in the early stages of the Solar System.

    • Matteo Massironi
    • Emanuele Simioni
    • Jean-Baptiste Vincent
    Research
    Nature
    Volume: 526, P: 402-405

  • The size and spatial distribution of pits on comet 67P/Churyumov–Gerasimenko, which are active and probably created by a sinkhole process, imply that large heterogeneities exist in the physical, structural or compositional properties of the first few hundred metres below the current cometary surface.

    • Jean-Baptiste Vincent
    • Dennis Bodewits
    • Cecilia Tubiana
    Research
    Nature
    Volume: 523, P: 63-66

  • Copper is an essential trace element for eukaryotes and most prokaryotes, but it has toxic side effects, so the levels of intracellular free copper must be limited. Mass spectrometry has now been used to measure the apparent Cu(I)-binding affinities of a representative set of intracellular copper proteins involved in redox catalysis, in copper trafficking to and within different cellular compartments, and in copper storage. The results provide the thermodynamic basis for the kinetic processes that lead to the distribution of cellular copper.

    • Lucia Banci
    • Ivano Bertini
    • Peep Palumaa
    Research
    Nature
    Volume: 465, P: 645-648