Nature Search

The small CRL4^CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Transcription-Coupled Nucleotide Excision Repair (TC-NER) removes transcription-blocking DNA lesions. This study reveals that DDA1 is a crucial player in TC-NER, protecting transcription programs against genotoxic insults.

Diana A. Llerena Schiffmacher
Shun-Hsiao Lee
Alex Pines
ResearchOpen Access29 Jul 2024
Nature Communications

Volume: 15, P: 1-17
Circulating levels of prolactin in human breast cancer

N A Sheth
K J Ranadive
A R Sheth
Research01 Aug 1975
British Journal of Cancer

Volume: 32, P: 160-167
Oestradiol inhibition of collagenase role in uterine involution

J. N. RYAN
J. F. WOESSNER JUN.
Research05 Apr 1974
Nature

Volume: 248, P: 526-528
Effect of prolactin and bromocriptine on growth of transplanted hormone-dependent mouse mammary tumours

P Briand
S M Thorpe
J L Daehnfeldt
Research01 Jun 1977
British Journal of Cancer

Volume: 35, P: 816-821
Prediction of CYP2D6 phenotype from genotype across world populations

Andrea Gaedigk
Katrin Sangkuhl
J. Steven Leeder
ResearchOpen Access07 Jul 2016
Genetics in Medicine

Volume: 19, P: 69-76
Transcription-coupled DNA–protein crosslink repair by CSB and CRL4^CSA-mediated degradation

Three studies identify a transcription-coupled DNA–protein crosslink repair pathway that depends on the Cockayne syndrome proteins and the proteasome.

Marjolein van Sluis
Qing Yu
Jurgen A. Marteijn
ResearchOpen Access10 Apr 2024
Nature Cell Biology

Volume: 26, P: 770-783
Global hotspots of mycorrhizal fungal richness are poorly protected

Machine-learning algorithms trained on 25,000 geolocated soil samples are used to create high-resolution global maps of mycorrhizal fungi, revealing that less than 10% of their biodiversity hotspots are in protected areas.

Michael E. Van Nuland
Colin Averill
Johan van den Hoogen
ResearchOpen Access23 Jul 2025
Nature

Volume: 645, P: 414-422
Erratum: Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment

M M Jukić
N Opel
M Ingelman-Sundberg
Amendments and Corrections18 Apr 2017
Molecular Psychiatry

Volume: 22, P: 1224
Stretchable and suturable fibre sensors for wireless monitoring of connective tissue strain

A capacitive, fibre-like stretchable strain sensor, formed of two conductors in a double helical structure, can be combined with an inductive coil to create a wireless strain-sensing system for biomedical applications.

Jaehong Lee
Stephan J. Ihle
Janos Vörös
Research01 Apr 2021
Nature Electronics

Volume: 4, P: 291-301
Correction: Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Nicholas M Morton
Jasmina Beltram
Simon Horvat
Amendments and Corrections01 Apr 2018
Nature Medicine

Volume: 24, P: 525
Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Genetic analysis in mice selected for leanness has identified thiosulfate sulfurtransferase as a target for the treatment of diabetes.

Nicholas M Morton
Jasmina Beltram
Simon Horvat
Research06 Jun 2016
Nature Medicine

Volume: 22, P: 771-779
CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards

P Dorado
M G Sosa-Macias
A LLerena
Research11 May 2010
The Pharmacogenomics Journal

Volume: 11, P: 108-112
A Multicentric Brazilian Investigative Study of Copy Number Variations in Patients with Congenital Anomalies and Intellectual Disability

J. R. M. Ceroni
R. L. Dutra
C. A. Kim
ResearchOpen Access06 Sept 2018
Scientific Reports

Volume: 8, P: 1-8
Heterogeneous spectrum of mutations in the Fanconi anaemia group A gene

M Wijker
NV Morgan
CG Mathew
Research12 Mar 1999
European Journal of Human Genetics

Volume: 7, P: 52-59
Further clinical & cytogenetic delineation in Ip36 deletion syndrome

F R Varaas
M Ramos
J C Cabral de Almeida
Research Highlights01 Jan 2000
Genetics in Medicine

Volume: 2, P: 95
CENP-A confers a reduction in height on octameric nucleosomes

Centromere protein A (CENP-A) is a histone H3 variant that specifies centromere location. Their reduced height relative to canonical H3 nucleosomes suggested that CENP-A nucleosomes might be tetrameric, but new biophysical measurements of reconstituted nucleosomes show that CENP-A confers a reduction in height on octameric CENP-A nucleosomes.

Matthew D D Miell
Colin J Fuller
Robin C Allshire
Research05 May 2013
Nature Structural & Molecular Biology

Volume: 20, P: 763-765
Interethnic differences in the relevance of CYP2C9 genotype and environmental factors for diclofenac metabolism in Hispanics from Cuba and Spain

A Llerena
M Alvarez
L R Calzadilla
Research20 Aug 2013
The Pharmacogenomics Journal

Volume: 14, P: 229-234
Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population

B Almoguera
R Riveiro-Alvarez
C Ayuso
ResearchOpen Access03 Jan 2012
The Pharmacogenomics Journal

Volume: 13, P: 197-204
Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer

Michele Garioni
Viviane J. Tschan
Clémentine Le Magnen
ResearchOpen Access02 Nov 2023
npj Precision Oncology

Volume: 7, P: 1-13
Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis

Lisa Strug and colleagues report a genome-wide association study for meconium ileus in individuals with cystic fibrosis. Conventional genome-wide approaches identified variants in SLC26A9 and SLC6A14 associated with meconium ileus. The authors also performed a hypothesis-driven genome-wide association study (HD-GWAS) that upweighted 3,814 SNPs within 10 kb of 155 genes expressed in the apical plasma membrane. The HD-GWAS identified variants near SLC9A3 associated with meconium ileus.

Lei Sun
Johanna M Rommens
Lisa J Strug
Research01 Apr 2012
Nature Genetics

Volume: 44, P: 562-569
Severe growth retardation and limb anomalies in a boy with 47,XY,+r(7) and maternal uniparental disomy for chromosome 7

C S Stadter
J Stamberg
E A Wulfsberg
Research Highlights01 Jan 2000
Genetics in Medicine

Volume: 2, P: 95
Double and triple trisomy in spontaneous abortions: an older maternal age and earlier gestational age than seen in single trisomies

J Sullivan
R Yusef
R Naeem
Research Highlights01 Jan 2000
Genetics in Medicine

Volume: 2, P: 95
Personal exposure to PM_2.5 oxidative potential and its association to birth outcomes

Lucille Joanna S. Borlaza
Gaëlle Uzu
A. Morlot
Research11 Nov 2022
Journal of Exposure Science & Environmental Epidemiology

Volume: 33, P: 416-426
VEGF-related polymorphisms identified by GWAS and risk for major depression

T Xie
M G Stathopoulou
S Visvikis-Siest
ResearchOpen Access07 Mar 2017
Translational Psychiatry

Volume: 7, P: e1055
Influence of admixture components on CYP2C9*2 allele frequency in eight indigenous populations from Northwest Mexico

M Sosa-Macías
B P Lazalde-Ramos
A LLerena
Research29 Jan 2013
The Pharmacogenomics Journal

Volume: 13, P: 567-572
Neurological toxicity after phenytoin infusion in a pediatric patient with epilepsy: influence of CYP2C9, CYP2C19 and ABCB1 genetic polymorphisms

P Dorado
E López-Torres
A LLerena
Research29 May 2012
The Pharmacogenomics Journal

Volume: 13, P: 359-361
Pharmacogenomics Education: International Society of Pharmacogenomics Recommendations for Medical, Pharmaceutical, and Health Schools Deans of Education

D Gurwitz
J E Lunshof
S Wong
Research26 Apr 2005
The Pharmacogenomics Journal

Volume: 5, P: 221-225
The third annual meeting of the International Society of Pharmacogenomics (ISP): a joint meeting with the International Union of Nutritional Sciences (IUNS) task force on genetics and nutrition

L J Sheffield
News & Views26 Apr 2005
The Pharmacogenomics Journal

Volume: 5, P: 146-148
Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment

M M Jukić
N Opel
M Ingelman-Sundberg
Research29 Nov 2016
Molecular Psychiatry

Volume: 22, P: 1155-1163
Pharmacogenetic study of antipsychotic induced acute extrapyramidal symptoms in a first episode psychosis cohort: role of dopamine, serotonin and glutamate candidate genes

S Mas
P Gassó
Vicent Balanzá-Martínez
Research07 Jun 2016
The Pharmacogenomics Journal

Volume: 16, P: 439-445

Search

The small CRL4^CSA ubiquitin ligase component DDA1 regulates transcription-coupled repair dynamics

Circulating levels of prolactin in human breast cancer

Oestradiol inhibition of collagenase role in uterine involution

Effect of prolactin and bromocriptine on growth of transplanted hormone-dependent mouse mammary tumours

Prediction of CYP2D6 phenotype from genotype across world populations

Transcription-coupled DNA–protein crosslink repair by CSB and CRL4^CSA-mediated degradation

Global hotspots of mycorrhizal fungal richness are poorly protected

Erratum: Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment

Stretchable and suturable fibre sensors for wireless monitoring of connective tissue strain

Correction: Corrigendum: Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness

CYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards

A Multicentric Brazilian Investigative Study of Copy Number Variations in Patients with Congenital Anomalies and Intellectual Disability

Heterogeneous spectrum of mutations in the Fanconi anaemia group A gene

Further clinical & cytogenetic delineation in Ip36 deletion syndrome

CENP-A confers a reduction in height on octameric nucleosomes

Interethnic differences in the relevance of CYP2C9 genotype and environmental factors for diclofenac metabolism in Hispanics from Cuba and Spain

Association of common genetic variants with risperidone adverse events in a Spanish schizophrenic population

Patient-derived organoids identify tailored therapeutic options and determinants of plasticity in sarcomatoid urothelial bladder cancer

Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis

Severe growth retardation and limb anomalies in a boy with 47,XY,+r(7) and maternal uniparental disomy for chromosome 7

Double and triple trisomy in spontaneous abortions: an older maternal age and earlier gestational age than seen in single trisomies

Personal exposure to PM_2.5 oxidative potential and its association to birth outcomes

VEGF-related polymorphisms identified by GWAS and risk for major depression

Influence of admixture components on CYP2C92* allele frequency in eight indigenous populations from Northwest Mexico

Neurological toxicity after phenytoin infusion in a pediatric patient with epilepsy: influence of CYP2C9, CYP2C19 and ABCB1 genetic polymorphisms

Pharmacogenomics Education: International Society of Pharmacogenomics Recommendations for Medical, Pharmaceutical, and Health Schools Deans of Education

The third annual meeting of the International Society of Pharmacogenomics (ISP): a joint meeting with the International Union of Nutritional Sciences (IUNS) task force on genetics and nutrition

Elevated CYP2C19 expression is associated with depressive symptoms and hippocampal homeostasis impairment

Pharmacogenetic study of antipsychotic induced acute extrapyramidal symptoms in a first episode psychosis cohort: role of dopamine, serotonin and glutamate candidate genes

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