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Showing 1–50 of 51 results

Advanced filters: Author: J. Hawkey Clear advanced filters

Vegetation recovery following retrogressive thaw slumps across northern tundra regions

Retrogressive thaw slumps are a key disturbance resulting from permafrost thaw that impact both vegetation and soil carbon. This study assesses surface greenness recovery times following thaw and shows that recovery can be predicted based on annual ecosystem gross primary productivity.

Zhuoxuan Xia
Lin Liu
Mark J. Lara
ResearchOpen Access30 Mar 2026
Nature Climate Change

Volume: 16, P: 606-612
Cross-reactive anti-prophage antibodies and bacterial heteroresistance implicated in phage therapeutic failure

A 22-year-old patient with cystic fibrosis and chronic, drug-resistant Bordetella bronchialis infection received compassionate-use phage therapy. Serum samples revealed that pre-existing antiphage immunity existed before treatment, indicating that future studies must evaluate antiphage immunity across the entire treatment regimen.

F. Gordillo Altamirano
D. Subedi
A. Y. Peleg
Research24 Apr 2026
Nature Medicine

P: 1-12
Bacterial contamination of intraocular lenses: the source of the bacteria

S R Spencer
S F Dealler
B A Noble
Research01 Nov 1989
Eye

Volume: 3, P: 685-689
A Possible Homeostatic Mechanism in Complement Fixation: Inhibition of the Activity of Fixed C′₁ By The Fixation Of C′_3a

P. J. LACHMANN
Research09 Apr 1966
Nature

Volume: 210, P: 140-141
Patterns of reactivity of the monoclonal antibody 791T/36 with different tumour metastases in the liver

C J Hawkey
C H Holmes
R W Baldwin
Research01 Dec 1986
British Journal of Cancer

Volume: 54, P: 871-875
Influence of Serum Factors on the Species-specificity of Tissue Thrombo-plastin

CHRISTINE HAWKEY
J. L. STAFFORD
Research26 Aug 1961
Nature

Volume: 191, P: 920-921
Surface Ultrastructure of Platelets and Thrombocytes

J. A. CLARKE
C. HAWKEY
A. J. SALSBURY
Research26 Jul 1969
Nature

Volume: 223, P: 401
Eleven-month “Embryonic Diapause” Marsupial

PATRICIA J. BERGER
Research23 Jul 1966
Nature

Volume: 211, P: 435-436
Cyclo-oxygenase inhibition reduces tumour growth and metastasis in an orthotopic model of breast cancer

E M Connolly
J H Harmey
D J Bouchier-Hayes
ResearchOpen Access09 Jul 2002
British Journal of Cancer

Volume: 87, P: 231-237
No Room for Mus

J. L. STAFFORD
Books & Arts23 Jul 1971
Nature

Volume: 232, P: 284
Lack of biochemical polymorphism in British fallow deer

J M Pemberton
R H Smith
Research01 Oct 1985
Heredity

Volume: 55, P: 199-207
Global population structure and genotyping framework for genomic surveillance of the major dysentery pathogen, Shigella sonnei

Whole genome sequencing is increasingly being adopted for Shigella sonnei outbreak investigation and surveillance, but there is no global classification standard. Here, the authors develop and validate a genomic framework implemented using open-source software, and demonstrate its application using surveillance data.

Jane Hawkey
Kalani Paranagama
Kathryn E. Holt
ResearchOpen Access11 May 2021
Nature Communications

Volume: 12, P: 1-12
Human fibrinogen possesses binding site for staphylococci on Aα and Bβ polypeptide chains

J. HAWIGER
D. K. HAMMOND
S. TIMMONS
Research01 Dec 1975
Nature

Volume: 258, P: 643-645
SNAP-mediated protein–protein interactions essential for neurotransmitter release

W. M. DeBello
V. O'Connor
G. J. Augustine
Research16 Feb 1995
Nature

Volume: 373, P: 626-630
Lens epithelial cells adhere less to HEMA than to PMMA intraocular lenses

R C Humphry
S P Ball
W J C C Rich
Research01 Jan 1991
Eye

Volume: 5, P: 66-69
Inhibition of neurotransmitter release by C2-domain peptides implicates synaptotagmin in exocytosis

Kurt Bommert
Milton P. Charlton
George J. Augustine
Research13 May 1993
Nature

Volume: 363, P: 163-165
Prof. K. J. Franklin

F. J. AUMONIER
Comments & Opinion23 Jul 1966
Nature

Volume: 211, P: 353
Phylogeographical analysis of the dominant multidrug-resistant H58 clade of Salmonella Typhi identifies inter- and intracontinental transmission events

Vanessa Wong and colleagues report whole-genome sequencing of 1,832 Salmonella enterica serovar Typhi isolates from 63 endemic countries. They identify mutations that define the multidrug resistant (MDR) H58 lineage and report numerous inter- and intracontinental transmissions of this lineage as well as an ongoing MDR typhoid epidemic in Africa.

Vanessa K Wong
Stephen Baker
Gordon Dougan
Research11 May 2015
Nature Genetics

Volume: 47, P: 632-639
Dysfunctional Plasminogen in Full-Term Newborn

A Estelles
J Aznar
J J Parrilla
Research01 Nov 1980
Pediatric Research

Volume: 14, P: 1180-1185
Early and rapid perceptual learning

David J C Hawkey
Sygal Amitay
David R Moore
Research07 Sept 2004
Nature Neuroscience

Volume: 7, P: 1055-1056
Forecasting global coral bleaching

Predicting coral bleaching is critical to better manage and preserve coral reefs from global warming. An impressive coordination of surveys across oceans now offers new metrics to help to predict coral bleaching events on a global scale.

Mathieu Pernice
David J. Hughes
News & Views30 Sept 2019
Nature Climate Change

Volume: 9, P: 803-804
Erratum: Global phylogeography and evolutionary history of Shigella dysenteriae type 1

Elisabeth Njamkepo
Nizar Fawal
François-Xavier Weill
Amendments and Corrections03 Oct 2016
Nature Microbiology

Volume: 1, P: 1
Genomic dissection of endemic carbapenem resistance reveals metallo-beta-lactamase dissemination through clonal, plasmid and integron transfer

Resistance to carbapenems, a class of last-line antibiotics, is a global health threat. This study analysed a two-decade history of carbapenem resistance and identified complex, multi-level (bacterial strain, plasmid, gene) transmission dynamics.

Nenad Macesic
Jane Hawkey
Anton Y. Peleg
ResearchOpen Access08 Aug 2023
Nature Communications

Volume: 14, P: 1-12
Interaction between nonsteroidal anti-inflammatory drug intake and calcium-channel blocker-based antihypertensive treatment in the Syst-Eur trial

H Celis
L Thijs
RH Fagard
Research07 Sept 2001
Journal of Human Hypertension

Volume: 15, P: 613-618
Exploring the genetic architecture of inflammatory bowel disease by whole-genome sequencing identifies association at ADCY7

Carl Anderson, Jeffrey Barrett and colleagues use whole-genome sequencing and imputation to explore the genetic architecture of inflammatory bowel disease. They identify a low-frequency missense variant in ADCY7 that doubles risk of ulcerative colitis and detect a burden of very rare, damaging missense variants in known Crohn's disease risk genes.

Yang Luo
Katrina M de Lange
Carl A Anderson
Research09 Jan 2017
Nature Genetics

Volume: 49, P: 186-192
Antimetastatic activity of a cyclooxygenase-2 inhibitor

G Roche-Nagle
E M Connolly
J H Harmey
ResearchOpen Access22 Jun 2004
British Journal of Cancer

Volume: 91, P: 359-365
The Influence of Fibrin Formation on the Transplantability of Murine Tumour Cells: Implications for the Mechanism of the Révész Effect

L J Peters
H B Hewitt
Research01 Apr 1974
British Journal of Cancer

Volume: 29, P: 279-291
An extended genotyping framework for Salmonella enterica serovar Typhi, the cause of human typhoid

Typhoid fever is caused by Salmonella enterica serovar Typhi (S. Typhi). This study examines ∼2,000 clinical isolates of S. Typhi to show highly structured/geographically restricted genomes except rapidly disseminating H58 subclade, and design a genotyping framework for tracking the disease.

Vanessa K. Wong
Stephen Baker
Ben Amos
ResearchOpen Access05 Oct 2016
Nature Communications

Volume: 7, P: 1-11
Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

Adult forms of inflammatory bowel disease (IBD) are of a polygenic nature, but paediatric and very early onset (VEO) IBD also occur as monogenic forms. Here, using whole exome sequencing, the authors explore both the monogenic and polygenic contribution to VEO-IBD and characterize a rare somatic mosaic VEO-IBD patient.

Eva Gonçalves Serra
Tobias Schwerd
Carl A. Anderson
ResearchOpen Access21 Feb 2020
Nature Communications

Volume: 11, P: 1-15
A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

While hundreds of loci are linked with inflammatory bowel diseases (IBDs), the functional consequences of the associated variants remain unclear. Here, the authors screened in ulcerative colitis (UC) patients’ genomes for protein-truncating variants near IBD loci, and identify a protein truncating variant in RNF186to be protective against UC.

Manuel A. Rivas
Daniel Graham
Mark J. Daly
ResearchOpen Access09 Aug 2016
Nature Communications

Volume: 7, P: 1-8
IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes

Most of the more than 200 known genetic risk loci for inflammatory bowel disease (IBD) reside in regulatory regions. Here, the authors provide eQTL datasets for six circulating immune cell types and ileal, colonic and rectal biopsies to map regulatory modules and identify potential causative genes for IBD.

Yukihide Momozawa
Julia Dmitrieva
Michel Georges
ResearchOpen Access21 Jun 2018
Nature Communications

Volume: 9, P: 1-18
Global phylogeography and evolutionary history of Shigella dysenteriae type 1

Global phylogenetic analyses of Shigella dysenteriae isolates uncover the transcontinental transmission events and evolution of antibiotic resistance behind the major dysentery epidemics in the modern era.

Elisabeth Njamkepo
Nizar Fawal
François-Xavier Weill
Research21 Mar 2016
Nature Microbiology

Volume: 1, P: 1-10
Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits

H M W Verheul
D Panigrahy
R J D’Amato
ResearchOpen Access11 Dec 1998
British Journal of Cancer

Volume: 79, P: 114-118
Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease

A meta-analysis of previous genome-wide association studies of Crohn’s disease and ulcerative colitis, the two most common forms of inflammatory bowel disease, with a combined total of more than 75,000 cases and controls, finds that most loci contribute to both phenotypes and other immune-mediated disorders.

Luke Jostins
Stephan Ripke
Judy H Cho
Research31 Oct 2012
Nature

Volume: 491, P: 119-124
Acute acalculous cholecystitis in patients with acute traumatic spinal cord injury

Francisco J Romero Ganuza
Faustino La Banda
Jesús Mazaira
Research01 Feb 1997
Spinal Cord

Volume: 35, P: 124-128
Erratum: A protein-truncating R179X variant in RNF186 confers protection against ulcerative colitis

Manuel A. Rivas
Daniel Graham
Mark J. Daly
Amendments and CorrectionsOpen Access13 Sept 2016
Nature Communications

Volume: 7, P: 1
Chemoprevention of intestinal tumorigenesis by nabumetone: induction of apoptosis and Bcl-2 downregulation

H K Roy
W J Karoski
T C Smyrk
ResearchOpen Access15 May 2001
British Journal of Cancer

Volume: 84, P: 1412-1416
Genome-wide association study implicates immune activation of multiple integrin genes in inflammatory bowel disease

Jeffrey Barrett, Carl Anderson and colleagues report the results of a large genome-wide association study of inflammatory bowel disease. They identify 25 new genome-wide significant loci, 3 of which contain integrin genes, and find that the associated variants at several of these loci are correlated with expression changes in response to immune stimulus.

Katrina M de Lange
Loukas Moutsianas
Jeffrey C Barrett
Research09 Jan 2017
Nature Genetics

Volume: 49, P: 256-261
Emergence and global spread of epidemic healthcare-associated Clostridium difficile

Trevor Lawley and colleagues report whole-genome sequencing of a large global collection of Clostridium difficile, the most common cause of healthcare-associated infection in the developed world. Their phylogenetic analysis traces the spread of this pathogen through healthcare-associated epidemics worldwide.

Miao He
Fabio Miyajima
Trevor D Lawley
Research09 Dec 2012
Nature Genetics

Volume: 45, P: 109-113
Amphiregulin acts as an autocrine growth factor in two human polarizing colon cancer lines that exhibit domain selective EGF receptor mitogenesis

L Damstrup
S K Kuwada
R J Coffey Jr
ResearchOpen Access07 May 1999
British Journal of Cancer

Volume: 80, P: 1012-1019
Cytokine-mediated nitric oxide release – a common cytotoxic pathway in host-versus-graft and graft-versus-host reactions?

A Vora
J Monaghan
D Crowther
Research01 Sept 1997
Bone Marrow Transplantation

Volume: 20, P: 385-389
Recombinant human lactoferrin ingestion attenuates indomethacin-induced enteropathy in vivo in healthy volunteers

F J Troost
W H M Saris
R-J M Brummer
Research28 Nov 2003
European Journal of Clinical Nutrition

Volume: 57, P: 1579-1585
Nested case–control study of the effects of non-steroidal anti-inflammatory drugs on breast cancer risk and stage

C R Sharpe
J-P Collet
J A Hanley
ResearchOpen Access06 Jun 2000
British Journal of Cancer

Volume: 83, P: 112-120
High-density mapping of the MHC identifies a shared role for HLA-DRB1*01:03 in inflammatory bowel diseases and heterozygous advantage in ulcerative colitis

John Rioux, Andre Franke, Tom Karlsen and colleagues perform a fine-mapping study of the HLA region in Crohn's disease and ulcerative colitis. They identify a primary role for HLA-DRB1*01:03 in both diseases and find evidence of heterozygous advantage in protection against ulcerative colitis.

Philippe Goyette
Gabrielle Boucher
John D Rioux
Research05 Jan 2015
Nature Genetics

Volume: 47, P: 172-179
Author Correction: Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease

Eva Gonçalves Serra
Tobias Schwerd
Carl A. Anderson
Amendments and CorrectionsOpen Access22 Jun 2022
Nature Communications

Volume: 13, P: 1
Species interactions constrain adaptation and preserve ecological stability in an experimental microbial community

Jake N. Barber
Luke C. Nicholson
Michael J. McDonald
ResearchOpen Access22 Jan 2022
The ISME Journal

Volume: 16, P: 1442-1452
Navigating my career in lipid research

Andrew J. Sinclair
ReviewsOpen Access27 May 2024
European Journal of Clinical Nutrition

Volume: 79, P: 1-6
NOX1 loss-of-function genetic variants in patients with inflammatory bowel disease

T Schwerd
R V Bryant
H H Uhlig
ResearchOpen Access01 Nov 2017
Mucosal Immunology

Volume: 11, P: 562-574
Validated predictive modelling of the environmental resistome

Gregory CA Amos
Emma Gozzard
Elizabeth M H Wellington
ResearchOpen Access13 Feb 2015
The ISME Journal

Volume: 9, P: 1467-1476
Haematopoietic SCT in severe autoimmune diseases: updated guidelines of the European Group for Blood and Marrow Transplantation

J A Snowden
R Saccardi
D Farge
Special FeaturesOpen Access17 Oct 2011
Bone Marrow Transplantation

Volume: 47, P: 770-790

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