Nature Search

Be swift, my darling

There's no escaping fate.

John Moran
Comments & Opinion25 May 2011
Nature

Volume: 473, P: 550
A benchmark of expert-level academic questions to assess AI capabilities

Humanity’s Last Exam, a multi-modal benchmark at the frontier of human knowledge, is designed to be an expert-level closed-ended academic benchmark with broad subject coverage.

Long Phan
Alice Gatti
Davide Scaramuzza
ResearchOpen Access28 Jan 2026
Nature

Volume: 649, P: 1139-1146
Initial Spread of Myxomatosis in Australia

JOHN LE GAY BRERETON
Research18 Jul 1953
Nature

Volume: 172, P: 108-110
Global insights into water resources, climate change and governance

The high levels of water extraction from the Colorado, Murray, Orange and Yellow rivers are shown to be the main cause of reduced flows in these systems. Changes in governance are urgently required to preserve the health of these rivers, especially in light of the present and future impacts of climate change.

R. Quentin Grafton
Jamie Pittock
John Quiggin
Reviews25 Nov 2012
Nature Climate Change

Volume: 3, P: 315-321
Extensive wet episodes in Late Glacial Australia resulting from high-latitude forcings

Germain Bayon
Patrick De Deckker
Marc D. Norman
ResearchOpen Access08 Mar 2017
Scientific Reports

Volume: 7, P: 1-7
Scavenging by threatened turtles regulates freshwater ecosystem health during fish kills

Claudia Santori
Ricky-John Spencer
James U. Van Dyke
ResearchOpen Access17 Sept 2020
Scientific Reports

Volume: 10, P: 1-7
TOR and heat shock response pathways regulate peroxisome biogenesis during proteotoxic stress

Here, the authors show that peroxisome proliferation is a conserved response to proteotoxic stress that occurs through stimulation of biogenesis and mediated by TOR and HSR signaling. Importantly, peroxisomes enable survival to proteotoxic stress.

Nandini Shukla
Maxwell L. Neal
Suresh Subramani
ResearchOpen Access28 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Abrupt vegetation change after the Late Quaternary megafaunal extinction in southeastern Australia

The extinction of megafauna in Australia about 43,000 years ago has been linked to both human arrival and vegetation change. Marine sediment analyses from the east coast of Australia suggest that vegetation change was a result, rather than cause, of the extinction.

Raquel A. Lopes dos Santos
Patrick De Deckker
Stefan Schouten
Research01 Jul 2013
Nature Geoscience

Volume: 6, P: 627-631
Climate impacts of the El Niño–Southern Oscillation on Australia

El Niño–Southern Oscillation (ENSO) profoundly affects Australian weather, climate, ecosystems and socio-economic sectors. This Review presents the progress made in understanding ENSO teleconnections to Australian weather over the past 40 years, describing the atmospheric dynamics, complexities and impacts of this climate phenomenon.

Andréa S. Taschetto
Shayne McGregor
Xuebin Zhang
Reviews04 Dec 2025
Nature Reviews Earth & Environment

P: 1-21
Multistage protective anti-CelTOS monoclonal antibodies with cross-species sterile protection against malaria

Cell-traversal protein for ookinetes and sporozoites (CelTOS) is a malaria vaccine candidate. Here, the authors characterize mouse monoclonal antibodies recognizing different CelTOS epitopes, and demonstrate protection from transgenic parasites containing P. falciparum or P. vivax as well as multistage activity.

Wai Kwan Tang
Nichole D. Salinas
Niraj H. Tolia
ResearchOpen Access29 Aug 2024
Nature Communications

Volume: 15, P: 1-14
Antlers—The Bones of Contention

JOHN HENSHAW
Research06 Dec 1969
Nature

Volume: 224, P: 1036-1037
Human predation contributed to the extinction of the Australian megafaunal bird Genyornis newtoni ∼47 ka

The impact of humans on megafaunal extinction is Australia is unclear. Here, the authors show burn patterns on eggshells of the extinct megafaunal bird, Genyornis newtoni, created by humans across Australia, suggesting that human predation contributed to the extinction of this bird around 47 thousand years ago.

Gifford Miller
John Magee
Stephen DeVogel
ResearchOpen Access29 Jan 2016
Nature Communications

Volume: 7, P: 1-7
Terrain, Traffic and Tundra

DAVID BELLAMY
JOHN RADFORTH
N. W. RADFORTH
Research18 Jun 1971
Nature

Volume: 231, P: 429-432
Adenovirus-mediated expression of HSV1-TK or Fas ligand induces cell death in primary human glioma-derived cell cultures that are resistant to the chemotherapeutic agent CCNU

Tricia C Maleniak
John L Darling
Maria G Castro
Research11 Sept 2001
Cancer Gene Therapy

Volume: 8, P: 589-598
Aerial surveys of waterbirds in Australia

Richard T. Kingsford
John L. Porter
Sharon Ryall
ResearchOpen Access10 Jun 2020
Scientific Data

Volume: 7, P: 1-6
Hereditary spherocytosis associated with deletion of human erythrocyte ankyrin gene on chromosome 8

Samuel E. Lux
William T. Tse
Bernard G. Forget
Research21 Jun 1990
Nature

Volume: 345, P: 736-739
Boundary complexity of cortical and subcortical areas predicts deep brain stimulation outcomes in Parkinson’s disease

This study shows that structural complexity of cortical and subcortical areas, measured from standard anatomical MRI, can predict Parkinson’s patient response to deep brain stimulation using advanced hypergraph modeling techniques.

Devin Schoen
Skyler Deutsch
Melanie A. Morrison
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-14
Integration of spatial and single-cell data across modalities with weakly linked features

MaxFuse enables data integration between modalities even when features are weakly correlated.

Shuxiao Chen
Bokai Zhu
Zongming Ma
ResearchOpen Access07 Sept 2023
Nature Biotechnology

Volume: 42, P: 1096-1106
Genomic evidence of hybridization between two independent invasions of European green crab (Carcinus maenas) in the Northwest Atlantic

N W Jeffery
C DiBacco
I R Bradbury
Research19 Apr 2017
Heredity

Volume: 119, P: 154-165
FYN regulates aqueous humor outflow and IOP through the phosphorylation of VE-CADHERIN

In the eye, intraocular pressure (IOP) regulation is critical for proper vision. High IOP can result in glaucoma a blinding disease. Here the authors show that tyrosine kinase FYN controls IOP by phosphorylating VE-cadherin, a key component in cell junctions.

Krishnakumar Kizhatil
Graham M. Clark
Simon W. M. John
ResearchOpen Access02 Jan 2025
Nature Communications

Volume: 16, P: 1-14
Action of Thionyl Chloride on Carboxylic Acids in Presence of Pyridine

J. P. E. HUMAN
JOHN A. MILLS
Research14 Dec 1946
Nature

Volume: 158, P: 877
Scientific Correspondence of the late Sir George Stokes

J. LARMOR
Research11 May 1905
Nature

Volume: 72, P: 29
The Fertilising Influence of Sunlight

JOHN AITKEN
Research10 Mar 1910
Nature

Volume: 83, P: 37
Four distinct trajectories of tau deposition identified in Alzheimer’s disease

Systematic characterization of longitudinal tau variability in human Alzheimer’s disease using an unbiased subtyping algorithm reveals four trajectories of tau deposition with distinct clinical features.

Jacob W. Vogel
Alexandra L. Young
Oskar Hansson
Research29 Apr 2021
Nature Medicine

Volume: 27, P: 871-881
Increased Amazon carbon emissions mainly from decline in law enforcement

Comparison of the carbon balance during 2010–2018 with 2019 and 2020 shows that a decline in law enforcement may have led to an increase in Amazon forest carbon emissions.

Luciana V. Gatti
Camilla L. Cunha
Guilherme B. M. Machado
Research23 Aug 2023
Nature

Volume: 621, P: 318-323
Broad fault zones enable deep fluid transport and limit earthquake magnitudes

Geophysical data from Chain Transform Fault reveal that broad damage zones preferentially facilitate fluid transport that cools the mantle, increasing earthquake depths. Fluids weaken the fault and segment it, limiting earthquake magnitudes.

Konstantinos Leptokaropoulos
Catherine A. Rychert
Satish C. Singh
ResearchOpen Access16 Sept 2023
Nature Communications

Volume: 14, P: 1-11
Growth of Ectromelia Virus in the Liver Parenchymal Cells of Different Strains of Mouse

J. A. ROBERTS
Research13 Jun 1964
Nature

Volume: 202, P: 1140-1141
Prefusion-stabilized SARS-CoV-2 S2-only antigen provides protection against SARS-CoV-2 challenge

Broadly protective vaccines are needed to combat current and future human coronaviruses. Here the authors use structure-based design to engineer spike S2-only antigens that provide partial protection from sarbecovirus challenge in mice.

Ching-Lin Hsieh
Sarah R. Leist
Jason S. McLellan
ResearchOpen Access20 Feb 2024
Nature Communications

Volume: 15, P: 1-14
Optimization of therapeutic antibodies for reduced self-association and non-specific binding via interpretable machine learning

Interpretable machine-learning models can identify clinical-stage monoclonal antibodies with optimal combinations of low off-target binding and low self-association in physiological and antibody-formulation conditions.

Emily K. Makowski
Tiexin Wang
Peter M. Tessier
Research04 Sept 2023
Nature Biomedical Engineering

Volume: 8, P: 45-56
How proteins bind macrocycles

Macrocycles have the potential to act on currently undruggable targets, but their discovery thus far has been unsystematic. A physicochemical analysis of all nonredundant co-crystal structures now sets out guidelines for macrocycle development.

Elizabeth A Villar
Dmitri Beglov
Adrian Whitty
Research20 Jul 2014
Nature Chemical Biology

Volume: 10, P: 723-731
Grassland intensification effects cascade to alter multifunctionality of wetlands within metaecosystems

It is not clear how agricultural intensification affects spatially coupled ecosystems. Here, the authors use long-term datasets on managed grasslands coupled with unmanaged wetlands showing that grassland intensification affects ecosystem service multifunctionality of spatially coupled wetlands

Yuxi Guo
Elizabeth H. Boughton
Jiangxiao Qiu
ResearchOpen Access13 Dec 2023
Nature Communications

Volume: 14, P: 1-15
Evidence for fungi and gold redox interaction under Earth surface conditions

The role of fungi in the biogeochemical cycling of gold remains unclear. Here the authors show that fungi can initiate gold oxidation under supergene conditions, thereby impacting gold mobilisation and secondary deposit formation in terrestrial environments.

Tsing Bohu
Ravi Anand
Mike Verrall
ResearchOpen Access23 May 2019
Nature Communications

Volume: 10, P: 1-13
A γδ T cell–IL-3 axis controls allergic responses through sensory neurons

A γδ T cell–IL-3 signalling axis is defined that controls the allergen responsiveness of cutaneous sensory neurons, leading to evidence for an immune rheostat that governs sensory neuronal responses to allergens on first exposure.

Cameron H. Flayer
Isabela J. Kernin
Caroline L. Sokol
Research04 Sept 2024
Nature

Volume: 634, P: 440-446
Disclaimer

JOHN DARLING
Correspondence09 Feb 1989
Nature

Volume: 337, P: 497
Real-time environmental surveillance of SARS-CoV-2 aerosols

Rapid detection of respiratory pathogens circulating in indoor environments could facilitate improved infection prevention responses. In this proof-of-concept study, the authors develop a pathogen air quality monitor for real-time direct detection of SARS-CoV-2 aerosols and demonstrate its application in rooms of people with SARS-CoV-2 infections.

Joseph V. Puthussery
Dishit P. Ghumra
Rajan K. Chakrabarty
ResearchOpen Access10 Jul 2023
Nature Communications

Volume: 14, P: 1-7
Factors controlling emission of dimethylsulphide from salt marshes

John W. H. Dacey
Gary M. King
Stuart G. Wakeham
Research23 Dec 1987
Nature

Volume: 330, P: 643-645
Zfy gene expression patterns are not compatible with a primary role in mouse sex determination

Peter Koopman
John Gubbay
Robin Lovell-Badge
Research28 Dec 1989
Nature

Volume: 342, P: 940-942
Facultative sex ratios and population dynamics

JOHN H. WERREN
ERIC L. CHARNOV
Research01 Mar 1978
Nature

Volume: 272, P: 349-350
Mislocalization of ΔF508 CFTR in cystic fibrosis sweat gland

Norbert Kartner
Olga Augustinas
John R. Riordan
Research01 Aug 1992
Nature Genetics

Volume: 1, P: 321-327
Complex landscapes of somatic rearrangement in human breast cancer genomes

Multiple somatic rearrangements are often found in cancer genomes, but the underlying processes of rearrangement and the effects of this are unclear. A paired-end sequencing strategy is now used to map somatic rearrangements in human breast cancer genomes. More rearrangements in some breast cancers are found than previously recognized, including frequent tandem duplications that may reflect a specific defect in DNA maintenance.

Philip J. Stephens
David J. McBride
Michael R. Stratton
Research24 Dec 2009
Nature

Volume: 462, P: 1005-1010
The chromatin regulator Ankrd11 controls cardiac neural crest cell-mediated outflow tract remodeling and heart function

Ankrd11 is a chromatin regulator that is strongly associated with KBG syndrome, a rare disorder that includes heart defects. Here they show that loss of Ankrd11 from neural crest dysregulates cardiac neural crest cell organization and crucial signaling pathways, leading to failed heart outflow tract septation and severe cardiac defects.

Yana Kibalnyk
Elia Afanasiev
Anastassia Voronova
ResearchOpen Access01 Jul 2024
Nature Communications

Volume: 15, P: 1-20
Combined analysis of the 12.8 and 15 μm JWST/MIRI eclipse observations of TRAPPIST-1 b

Simultaneous observations of TRAPPIST-1 b from JWST at 12.8 and 15 μm indicate that it is probably a bare rock with a mineral-rich surface. However, an alternative scenario with a CO₂-rich atmosphere and hazes could also explain the observations.

Elsa Ducrot
Pierre-Olivier Lagage
Gillian Wright
Research16 Dec 2024
Nature Astronomy

Volume: 9, P: 358-369
“Coal, and the Prevention of Explosions and Fires in Mines”

JOHN HARGER
Research29 May 1913
Nature

Volume: 91, P: 319-320
DNMT3A clonal hematopoiesis-driver mutations induce cardiac fibrosis by paracrine activation of fibroblasts

This study uncovers a critical link between DNMT3A-driven CHIP and heart failure and, in particular, it shows that DNMT3A inactivation in monocytes boosts the release of HB-EGF, which activates fibroblasts inducing diffuse fibrosis in the heart.

Mariana Shumliakivska
Guillermo Luxán
Stefanie Dimmeler
ResearchOpen Access19 Jan 2024
Nature Communications

Volume: 15, P: 1-20
A Review of the nutritional needs of Meals on Wheels consumers and factors associated with the provision of an effective Meals on Wheels service—an Australian perspective

J Krassie
C Smart
DCK Roberts
Reviews27 Mar 2000
European Journal of Clinical Nutrition

Volume: 54, P: 275-280
Macromolecular condensation buffers intracellular water potential

Water thermodynamics drive changes in macromolecular assembly that rapidly restore intracellular water availability in response to physiological fluctuations in temperature, pressure and osmotic strength.

Joseph L. Watson
Estere Seinkmane
Emmanuel Derivery
ResearchOpen Access18 Oct 2023
Nature

Volume: 623, P: 842-852
Next-Generation Morphometry for pathomics-data mining in histopathology

Pathology diagnostics still rely on tissue morphology assessment by trained experts. Here, the authors perform deep-learning-based segmentation followed by large-scale feature extraction of histological images, i.e., next-generation morphometry, to enable outcome-relevant and disease-specific pathomics analysis of non-tumor kidney pathology.

David L. Hölscher
Nassim Bouteldja
Peter Boor
ResearchOpen Access28 Jan 2023
Nature Communications

Volume: 14, P: 1-14
Spatial heterogeneity: evolved behaviour or mathematical artefact?

John A. Downing
Research18 Sept 1986
Nature

Volume: 323, P: 255-257
Analysis of function

John R. Krebs
Reviews18 Mar 1976
Nature

Volume: 260, P: 196-197
Social–environmental drivers inform strategic management of coral reefs in the Anthropocene

Surveys from 2,584 sites across the Indo-Pacific identify key climate, socioeconomic and environmental drivers associated with hard coral assemblages. This informs a strategic approach to protect, recover or transform coral reef management.

Emily S. Darling
Tim R. McClanahan
David Mouillot
Research12 Aug 2019
Nature Ecology & Evolution

Volume: 3, P: 1341-1350

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