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Gene Therapy (3)
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Showing 1–4 of 4 results

Advanced filters: Author: Jack W. Hickmott Clear advanced filters

MicroRNA-mediated neuronal detargeting alters astrocyte cell fate conversion trajectories in vivo

In vivo astrocyte-to-neuron conversion is driven by Ascl1^SA6 expression restricted to astrocytes via miR-124-target sites, with astrocyte pre-labeling marking reprogrammed neurons, confirmed by single-cell transcriptomics and pseudotime analysis.

Hussein Ghazale
Martin Parga Pazos
Carol Schuurmans
ResearchOpen Access05 Dec 2025
Communications Biology

Volume: 8, P: 1-14
Correction: Epistasis between Pax6^Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials

Jack W. Hickmott
Uvini Gunawardane
Elizabeth M. Simpson
Amendments and CorrectionsOpen Access02 Jan 2019
Gene Therapy

Volume: 26, P: 133
Human MiniPromoters for ocular-rAAV expression in ON bipolar, cone, corneal, endothelial, Müller glial, and PAX6 cells

Andrea J. Korecki
Jorge L. Cueva-Vargas
Elizabeth M. Simpson
ResearchOpen Access02 Feb 2021
Gene Therapy

Volume: 28, P: 351-372
Epistasis between Pax6^Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials

Jack W. Hickmott
Uvini Gunawardane
Elizabeth M. Simpson
ResearchOpen Access26 Sept 2018
Gene Therapy

Volume: 25, P: 524-537