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Showing 1–2 of 2 results
Advanced filters: Author: Jacquelyn Salzbank Clear advanced filters

  • Here authors reveal that placental hormone insufficiency can cause sex-linked brain inflammatory responses in mice. Altered microglial and prostaglandin signalling drive male-biased impairments, highlighting therapeutic targets for neurodevelopmental disorders.

    • Jacquelyn Salzbank
    • Helene Lacaille
    • Anna A. Penn
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-17

  • Placental dysfunction has been implicated in abnormal neurodevelopment. Vacher et al. found that loss of a neuroactive hormone from the placenta alters brain development in a regional and sex-linked manner, resulting in autism-like behaviors in male offspring.

    • Claire-Marie Vacher
    • Helene Lacaille
    • Anna A. Penn
    ResearchOpen Access
    Nature Neuroscience
    Volume: 24, P: 1392-1401