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Showing 1–3 of 3 results
Advanced filters: Author: Jada N. Walker Clear advanced filters

  • Here the authors present a non-FRET DNA-templated silver nanocluster probe that exhibits a distinct colour switch from green to red upon nuclease digestion, visible under UV excitation, offering a low-cost, effective alternative to fluorescent reporters for detecting nuclease activities.

    • Soonwoo Hong
    • Jada N. Walker
    • Hsin-Chih Yeh
    Research
    Nature Nanotechnology
    Volume: 19, P: 810-817

  • Here, Schwartz, Bravo, and Ahsan et al. show how multi-subunit fusion proteins are arranged around a crRNA in a type III CRISPR-Cas effector to cleave target RNA. Structures and molecular dynamics of this complex show three distinct active sites that can be used for programmable RNA cleavage.

    • Evan A. Schwartz
    • Jack P. K. Bravo
    • David W. Taylor
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-14