Senescent cells are typically identified by a combination of senescence-associated markers, and the phenotype is heterogeneous. Here, using deep neural networks, Heckenbach et al. show that nuclear morphology can be used to predict cellular senescence in images of tissues and cell cultures.
- Indra Heckenbach
- Garik V. Mkrtchyan
- Morten Scheibye-Knudsen
