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A SETD2–CDK1–lamin axis maintains nuclear morphology and genome stability

Khan et al. report a non-catalytic function of the methyltransferase SETD2 in regulating nuclear morphology and genome integrity. The SETD2 amino terminus functions as a scaffold helping CDK1 associate with lamins during nuclear-envelope disassembly

Abid Khan
Cheng Zhang
Brian D. Strahl
Research11 Aug 2025
Nature Cell Biology

Volume: 27, P: 1327-1341
Temperature and wavelength effects on the photochemistry of rhodopsin, isorhodopsin, bacteriorhodopsin and their photoproducts

JAMES B. HURLEY
THOMAS G. EBREY
MICHAEL OTTOLENGHI
Research08 Dec 1977
Nature

Volume: 270, P: 540-542

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A SETD2–CDK1–lamin axis maintains nuclear morphology and genome stability

Temperature and wavelength effects on the photochemistry of rhodopsin, isorhodopsin, bacteriorhodopsin and their photoproducts

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