In this Review, Borén and colleagues present insights into the role of apolipoprotein B-containing lipoproteins in atherogenesis, with an emphasis on the mechanisms leading to atherosclerotic plaque initiation and growth. They describe the causative role of LDL at the early stages of atherogenesis and discuss the relative atherogenicity of lipoprotein(a) and triglyceride-rich lipoproteins.
- Jan Borén
- Chris J. Packard
- Christoph J. Binder