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Showing 1–2 of 2 results
Advanced filters: Author: Jeffrey M. Malgady Clear advanced filters

  • Neural mechanisms underlying local striatal serotonin release are not fully understood. Here authors show that striatal cholinergic interneurons drive local serotonin release by activating nicotinic receptors on serotonergic axons in the dorsal but not ventral striatum. This mechanism expands the spatial range of serotonin release and is exaggerated in a mouse model of compulsive behavior.

    • Lior Matityahu
    • Zachary B. Hobel
    • Joshua A. Goldberg
    ResearchOpen Access
    Nature Communications
    Volume: 17, P: 1-9

  • The auditory striatum, the tail portion of dorsal striatum, is implicated in decision-making. This study uncovers a phasic mechanism within the nigrostriatal system that regulates auditory decisions by modulating ongoing auditory perception.

    • Allen P. F. Chen
    • Jeffrey M. Malgady
    • Qiaojie Xiong
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-15