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GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging

Jang and colleagues demonstrate that GDF3 reshapes the chromatin landscape of inflammatory adipose tissue macrophages and drives endotoxic inflammation with age. Pharmacological inhibition of the GDF3–SMAD2/3 axis alleviates endotoxemia lethality in old mice.

In Hwa Jang
Anna Carey
Christina D. Camell
ResearchOpen Access15 Dec 2025
Nature Aging

Volume: 6, P: 127-142
Breast implant-associated anaplastic large cell lymphoma: clinical follow-up and analysis of sequential pathologic specimens of untreated patients shows persistent or progressive disease

Mark G. Evans
L. Jeffrey Medeiros
Roberto N. Miranda
Research21 Jun 2021
Modern Pathology

Volume: 34, P: 2148-2153
The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

Khalid El Bairi
Harry R. Haynes
Paul J. Van Diest
ReviewsOpen Access01 Dec 2021
npj Breast Cancer

Volume: 7, P: 1-17

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GDF3 promotes adipose tissue macrophage-mediated inflammation via altered chromatin accessibility during aging

Breast implant-associated anaplastic large cell lymphoma: clinical follow-up and analysis of sequential pathologic specimens of untreated patients shows persistent or progressive disease

The tale of TILs in breast cancer: A report from The International Immuno-Oncology Biomarker Working Group

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