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Antibody responses to a Cryptosporidium parvum rCP15/60 vaccine

Alexandra Burton
Daryl Nydam
Dwight Bowman
ResearchOpen Access20 Nov 2009
Nature Precedings

P: 1
A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

The establishment of a drug-discovery screening pipeline for cryptosporidiosis, and identification of pyrazolopyridines as selective ATP-competitive inhibitors of the Cryptosporidium lipid kinase PI(4)K.

Ujjini H. Manjunatha
Sumiti Vinayak
Thierry T. Diagana
Research31 May 2017
Nature

Volume: 546, P: 376-380
Cryptosporidium PI(4)K inhibitor EDI048 is a gut-restricted parasiticidal agent to treat paediatric enteric cryptosporidiosis

EDI048 is a gastrointestinal-targeted Cryptosporidium PI(4)K inhibitor that undergoes a predictable metabolism and limits systemic exposure without compromising its anti-parasitic activity.

Ujjini H. Manjunatha
Suresh B. Lakshminarayana
Thierry T. Diagana
ResearchOpen Access08 Oct 2024
Nature Microbiology

Volume: 9, P: 2817-2835

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Antibody responses to a Cryptosporidium parvum rCP15/60 vaccine

A Cryptosporidium PI(4)K inhibitor is a drug candidate for cryptosporidiosis

Cryptosporidium PI(4)K inhibitor EDI048 is a gut-restricted parasiticidal agent to treat paediatric enteric cryptosporidiosis

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