Nature Search

Machine learning models predict long COVID outcomes based on baseline clinical and immunologic factors

Jayavelu, Samaha et al., apply machine learning models on hospital admission data, including antibody titers and viral load, to identify patients at high risk for Long COVID. Low antibody levels, high viral loads, chronic diseases, and female sex are key predictors, supporting early, targeted interventions.

Naresh Doni Jayavelu
Hady Samaha
Matthew C. Altman
ResearchOpen Access03 Jan 2026
Communications Medicine

Volume: 6, P: 1-10
Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients

Solid organ transplant recipients are at increased risk of infectious disease and have unique molecular pathophysiology. Here the authors use host-microbe profiling to assess SARS-CoV-2 infection and immunity in solid organ transplant recipients, showing enhanced viral abundance, impaired clearance, and increased expression of innate immunity genes.

Harry Pickering
Joanna Schaenman
Charles R. Langelier
ResearchOpen Access10 Jan 2025
Nature Communications

Volume: 16, P: 1-16
IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

The role of IgG glycosylation in the immune response has been studied, but less is known about IgM glycosylation. Here the authors characterize glycosylation of SARS-CoV-2 spike specific IgM and show that it correlates with COVID-19 severity and affects complement deposition.

Benjamin S. Haslund-Gourley
Kyra Woloszczuk
Mary Ann Comunale
ResearchOpen Access09 Jan 2024
Nature Communications

Volume: 15, P: 1-19
The Musculoskeletal Knowledge Portal: improving access to multi-omics data

Built by and for the research community, the Musculoskeletal Knowledge Portal (MSK-KP) offers researchers a single integrated platform on which to display, access, distill and explore results from large genomic and epigenomic studies to formulate hypotheses and accelerate the development of patient-centered therapeutics for complex, multi-factorial conditions such as osteoarthritis.

Jennifer J. Westendorf
Lynda F. Bonewald
Noël P. Burtt
Comments & Opinion22 Oct 2021
Nature Reviews Rheumatology

Volume: 18, P: 1-2
Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

Post-acute sequelae of SARS-CoV-2 (PASC) is still not well understood. Here the authors provide patient reported outcomes from 590 hospitalized COVID-19 patients and show association of PASC with higher respiratory SARS-CoV-2 load and circulating antibody titers, and in some an elevation in circulating fibroblast growth factor 21.

Al Ozonoff
Naresh Doni Jayavelu
Nadine Rouphael
ResearchOpen Access03 Jan 2024
Nature Communications

Volume: 15, P: 1-17
Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma

André Oliveira and colleagues identify a recurrent translocation in biphenotypic sinonasal sarcomas generating a PAX3-MAML3 fusion gene. The resulting protein is a potent transcriptional activator of PAX3 response elements and is associated with aberrant expression of genes involved in neuroectodermal and myogenic differentiation.

Xiaoke Wang
Krista L Bledsoe
André M Oliveira
Research25 May 2014
Nature Genetics

Volume: 46, P: 666-668
MicroRNA-101a enhances trabecular bone accrual in male mice

Amel Dudakovic
Sofia Jerez
Andre J. van Wijnen
ResearchOpen Access03 Aug 2022
Scientific Reports

Volume: 12, P: 1-18
Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice

Changli Zhang
Madeline P. Smith
Svenja Illien-Jünger
ResearchOpen Access03 Oct 2019
Cell Death & Disease

Volume: 10, P: 1-15
Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1

David H. H. Molstad
Elizabeth Zars
Elizabeth W. Bradley
ResearchOpen Access11 Dec 2020
Scientific Reports

Volume: 10, P: 1-15
CAML mediates survival of Myc-induced lymphoma cells independent of tail-anchored protein insertion

Jennifer C Shing
Lonn D Lindquist
Richard J Bram
ResearchOpen Access29 May 2017
Cell Death Discovery

Volume: 3, P: 1-11
The intersection of aging and estrogen in osteoarthritis

Aysegul Atasoy-Zeybek
Kelly K. Showel
Christopher H. Evans
ReviewsOpen Access25 Feb 2025
npj Women's Health

Volume: 3, P: 1-13

Search

Machine learning models predict long COVID outcomes based on baseline clinical and immunologic factors

Host-microbe multiomic profiling identifies distinct COVID-19 immune dysregulation in solid organ transplant recipients

IgM N-glycosylation correlates with COVID-19 severity and rate of complement deposition

The Musculoskeletal Knowledge Portal: improving access to multi-omics data

Features of acute COVID-19 associated with post-acute sequelae of SARS-CoV-2 phenotypes: results from the IMPACC study

Recurrent PAX3-MAML3 fusion in biphenotypic sinonasal sarcoma

MicroRNA-101a enhances trabecular bone accrual in male mice

Phlpp1 is associated with human intervertebral disc degeneration and its deficiency promotes healing after needle puncture injury in mice

Hdac3 deletion in myeloid progenitor cells enhances bone healing in females and limits osteoclast fusion via Pmepa1

CAML mediates survival of Myc-induced lymphoma cells independent of tail-anchored protein insertion

The intersection of aging and estrogen in osteoarthritis

Search

Quick links

Search

Filter By:

Search

Quick links