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ACKR1 genetic testing should be offered before starting clozapine treatment

This Perspective considers the addition of ACKR1 genetic testing for identifying ACKR1/DARC-associated neutropenia in patients receiving clozapine, recommending eligibility criteria and testing strategies while estimating substantial cost savings for the UK healthcare system and enhancing equitable treatment access.

Stephen Murtough
Daisy Mills
Elvira Bramon
Reviews07 Jan 2026
Nature Mental Health

Volume: 4, P: 30-41
Reproductive plasticity of Hawaiian Montipora corals following thermal stress

E. Michael Henley
Mariko Quinn
Mary Hagedorn
ResearchOpen Access09 Jun 2021
Scientific Reports

Volume: 11, P: 1-17
Optimized design parameters for CRISPR Cas9 and Cas12a homology-directed repair

Mollie S. Schubert
Bernice Thommandru
Garrett R. Rettig
ResearchOpen Access30 Sept 2021
Scientific Reports

Volume: 11, P: 1-15
Phylogenomics of Tetraopes longhorn beetles unravels their evolutionary history and biogeographic origins

Nayeli Gutiérrez-Trejo
Matthew H. Van Dam
James M. Carpenter
ResearchOpen Access27 Mar 2024
Scientific Reports

Volume: 14, P: 1-13
Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples

Roddy Walsh
Kate L. Thomson
Hugh Watkins
ResearchOpen Access17 Aug 2016
Genetics in Medicine

Volume: 19, P: 192-203

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