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Showing 51–100 of 117 results

Advanced filters: Author: Ji-Eun Lee Clear advanced filters

Vascular differentiation of multipotent spermatogonial stem cells derived from neonatal mouse testis

Ji-Eun Im
Sun-Hwa Song
Wonhee Suh
ResearchOpen Access19 Jan 2012
Experimental & Molecular Medicine

Volume: 44, P: 303-309
Replication fork stability confers chemoresistance in BRCA-deficient cells

Protection of nascent DNA from degradation provides a mechanism that can promote synthetic viability and drug resistance in Brca-deficient cells without restoring homologous recombination at double-strand breaks.

Arnab Ray Chaudhuri
Elsa Callen
André Nussenzweig
Research20 Jul 2016
Nature

Volume: 535, P: 382-387
Brd4 binds to active enhancers to control cell identity gene induction in adipogenesis and myogenesis

Despite being an important cancer drug target, the role of epigenetic reader Brd4 in cell differentiation and development remains unclear. Here, the authors provide evidence that Brd4 plays an important role in adipogenesis and myogenesis by binding to active enhancers to regulate gene expression.

Ji-Eun Lee
Young-Kwon Park
Kai Ge
ResearchOpen Access20 Dec 2017
Nature Communications

Volume: 8, P: 1-12
Depletion of Nsd2-mediated histone H3K36 methylation impairs adipose tissue development and function

The epigenetic mechanisms regulating adipose tissue development are poorly understood. Here the authors show that reduction of H3K36 methylation in preadipocytes, both by H3.3K36M expression and depletion of H3K36 methyltransferase Nsd2, impairs adipogenesis by increasing H3K27me3.

Lenan Zhuang
Younghoon Jang
Kai Ge
ResearchOpen Access04 May 2018
Nature Communications

Volume: 9, P: 1-15
Disruption of KMT2D perturbs germinal center B cell development and promotes lymphomagenesis

Two studies demonstrate that the methyltransferase KMT2D, which is recurrently mutated in several types of human B cell lymphoma, suppresses tumorigenesis by altering the epigenetic landscape of B cells; Kmt2d deletion in mice perturbs normal B cell development.

Jiyuan Zhang
David Dominguez-Sola
Laura Pasqualucci
Research14 Sept 2015
Nature Medicine

Volume: 21, P: 1190-1198
MLL4 prepares the enhancer landscape for Foxp3 induction via chromatin looping

Zhao and colleagues show that the histone lysine methyltransferase MLL4 primes the Foxp3 locus for transcriptional activation in thymus-derived and inducible regulatory T cells.

Katarzyna Placek
Gangqing Hu
Keji Zhao
Research31 Jul 2017
Nature Immunology

Volume: 18, P: 1035-1045
The histone lysine methyltransferase KMT2D sustains a gene expression program that represses B cell lymphoma development

Two studies demonstrate that the methyltransferase KMT2D, which is recurrently mutated in several types of human B cell lymphoma, suppresses tumorigenesis by altering the epigenetic landscape of B cells; Kmt2d deletion in mice perturbs normal B cell development.

Ana Ortega-Molina
Isaac W Boss
Hans-Guido Wendel
Research14 Sept 2015
Nature Medicine

Volume: 21, P: 1199-1208
The tidyomics ecosystem: enhancing omic data analyses

tidyomics offers a software ecosystem for omic data manipulation and analysis that bridges Bioconductor with the tidyverse framework.

William J. Hutchison
Timothy J. Keyes
Stefano Mangiola
Research14 Jun 2024
Nature Methods

Volume: 21, P: 1166-1170
From community to science to community, enhancing remote sensing of water quality in Chesapeake Bay tributaries through participatory science

Min-Sun Lee
Maria Tzortziou
Alison Cawood
ResearchOpen Access10 Aug 2025
Scientific Reports

Volume: 15, P: 1-20
The role of lean body mass in predicting mortality in hemodialysis patients across different age groups

Ji-Eun Kim
Jinyeong Yi
Seun Deuk Hwang
ResearchOpen Access16 Jan 2025
Scientific Reports

Volume: 15, P: 1-11
Distribution and pathogen prevalence of field-collected ticks from south-western Korea: a study from 2019 to 2022

Kwang gon Kim
Da jeong Hwang
Sun-hee Kim
ResearchOpen Access29 May 2024
Scientific Reports

Volume: 14, P: 1-12
Recent advances in organic luminescent materials with narrowband emission

Jung Min Ha
Seon Hyoung Hur
Han Young Woo
ReviewsOpen Access16 Jul 2021
NPG Asia Materials

Volume: 13, P: 1-36
Mutations in TMEM216 perturb ciliogenesis and cause Joubert, Meckel and related syndromes

Joseph Gleeson and colleagues report that mutations in TMEM216 cause Joubert, Meckel and related syndromes. They further show that TMEM216 localizes to the base of cilia and that its loss leads to defects in ciliogenesis and centrosome docking.

Enza Maria Valente
Clare V Logan
Joseph G Gleeson
Research30 May 2010
Nature Genetics

Volume: 42, P: 619-625
Preventive role of Pastinaca sativa in mitigating metabolic dysfunction-associated steatotic liver disease via modulation of metabolic endotoxemia

Ji-Eun Park
Hye-Bin Lee
Ho-Young Park
ResearchOpen Access06 Feb 2025
npj Science of Food

Volume: 9, P: 1-12
CEP41 is mutated in Joubert syndrome and is required for tubulin glutamylation at the cilium

Joseph Gleeson and colleagues identify CEP41 mutations as a cause of Joubert syndrome. Their functional studies suggest that CEP41 regulates ciliary entry of TTLL6, an enzyme required for tubulin glutamylation at the cilium.

Ji Eun Lee
Jennifer L Silhavy
Joseph G Gleeson
Research15 Jan 2012
Nature Genetics

Volume: 44, P: 193-199
Inhibition of highly pathogenic avian influenza (HPAI) virus by a peptide derived from vFLIP through its direct destabilization of viruses

Ho-Jin Moon
Chamilani Nikapitiya
Jong-Soo Lee
ResearchOpen Access07 Jul 2017
Scientific Reports

Volume: 7, P: 1-11
MicroRNA-548 regulates high mobility group box 1 expression in patients with preterm birth and chorioamnionitis

Ga-Hyun Son
Youngmi Kim
Young-Han Kim
ResearchOpen Access24 Dec 2019
Scientific Reports

Volume: 9, P: 1-12
Compound heterozygous mutations of SH3TC2 in Charcot–Marie–Tooth disease type 4C patients

Ah Jin Lee
Soo Hyun Nam
Ki Wha Chung
Research21 Jun 2019
Journal of Human Genetics

Volume: 64, P: 961-965
OASL1 deficiency promotes antiviral protection against genital herpes simplex virus type 2 infection by enhancing type I interferon production

Ji Eun Oh
Myeong Sup Lee
Heung Kyu Lee
ResearchOpen Access11 Jan 2016
Scientific Reports

Volume: 6, P: 1-13
Tumour-associated myeloid cells expressing IL-10R2/IL-22R1 as a potential biomarker for diagnosis and recurrence of pancreatic ductal adenocarcinoma

Hyung Keun Lee
So Young Kim
Dong Ki Lee
ResearchOpen Access20 Apr 2024
British Journal of Cancer

Volume: 130, P: 1979-1989
Evaluation of the effects of temperature and centrifugation time on elimination of uncured resin from 3D-printed dental aligners

Ji-Eun Kim
Utkarsh Mangal
Sung-Hwan Choi
ResearchOpen Access02 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Toxoplasma GRA16 attenuates Tau hyperphosphorylation and enhances autophagy in thrombin-treated HT-22 hippocampal neuronal cells

Seung-Hwan Seo
Do-Won Ham
Eun-Hee Shin
ResearchOpen Access20 May 2025
Scientific Reports

Volume: 15, P: 1-11
Ottogi Inhibits Wnt/β-catenin Signaling by Regulating Cell Membrane Trafficking of Frizzled8

Hyun-Taek Kim
Mi-Sun Lee
Cheol-Hee Kim
ResearchOpen Access16 Oct 2017
Scientific Reports

Volume: 7, P: 1-13
A novel pyrazole derivative protects from ovariectomy-induced osteoporosis through the inhibition of NADPH oxidase

Jung Hee Joo
Jeong-Eun Huh
Yun Soo Bae
ResearchOpen Access15 Mar 2016
Scientific Reports

Volume: 6, P: 1-14
Primary cilia mediate mitochondrial stress responses to promote dopamine neuron survival in a Parkinson’s disease model

Ji-Eun Bae
Gil Myung Kang
Dong-Hyung Cho
ResearchOpen Access16 Dec 2019
Cell Death & Disease

Volume: 10, P: 1-15
Fine particulate matter (PM2.5) inhibits ciliogenesis by increasing SPRR3 expression via c-Jun activation in RPE cells and skin keratinocytes

Ji-Eun Bae
Hyunjung Choi
Dong-Hyung Cho
ResearchOpen Access08 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Real-world evidence of constipation and laxative use in the Korean population with chronic kidney disease from a common data model

Kipyo Kim
Ji-Eun Kim
Joon Ho Song
ResearchOpen Access19 Mar 2024
Scientific Reports

Volume: 14, P: 1-9
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans

Caroline J. Breitbach
James Burke
David H. Kirn
Research31 Aug 2011
Nature

Volume: 477, P: 99-102
DNA-damage-induced differentiation of leukaemic cells as an anti-cancer barrier

Histone methyl-transferase MLL4 is required for stem-cell activity and an aggressive form of acute myeloid leukaemia harbouring the MLL–AF9 oncogene.

Margarida A. Santos
Robert B. Faryabi
André Nussenzweig
Research27 Jul 2014
Nature

Volume: 514, P: 107-111
Mapping intact protein isoforms in discovery mode using top-down proteomics

John C. Tran
Leonid Zamdborg
Neil L. Kelleher
Research30 Oct 2011
Nature

Volume: 480, P: 254-258
Associations between genetic polymorphisms of membrane transporter genes and prognosis after chemotherapy: meta-analysis and finding from Seoul Breast Cancer Study (SEBCS)

Ji-Eun Kim
Jaesung Choi
Ji-Yeob Choi
Research04 Apr 2018
The Pharmacogenomics Journal

Volume: 18, P: 633-645
Lactobacillus paracasei-derived extracellular vesicles reverse molecular and behavioral deficits in mouse models of autism spectrum disorder

Jin-Young Park
Eun-Hwa Lee
Pyung-Lim Han
ResearchOpen Access01 Apr 2025
Experimental & Molecular Medicine

Volume: 57, P: 788-803
A CRISPR-based base-editing screen for the functional assessment of BRCA1 variants

Jiyeon Kweon
An-Hee Jang
Yongsub Kim
ResearchOpen Access29 Aug 2019
Oncogene

Volume: 39, P: 30-35
Protein disulfide isomerase integrates toll-like receptor 4 and P2X7 receptor signaling pathways during lipopolysaccharide-induced neuroinflammation

Ji-Eun Kim
Su Hyeon Wang
Tae-Hyun Kim
ResearchOpen Access06 Mar 2025
Scientific Reports

Volume: 15, P: 1-15
Impact of BMI on peak growth hormone responses to provocative tests and therapeutic outcome in children with growth hormone deficiency

Aram Yang
Sung Yoon Cho
Ji-Eun Lee
ResearchOpen Access07 Nov 2019
Scientific Reports

Volume: 9, P: 1-10
STRAP Acts as a Scaffolding Protein in Controlling the TLR2/4 Signaling Pathway

Hyunbin D. Huh
Eun A. Ra
Boyoun Park
ResearchOpen Access09 Dec 2016
Scientific Reports

Volume: 6, P: 1-11
Network of biomarkers and their mediation effects on the associations between regular exercise and the incidence of cardiovascular & metabolic diseases

JooYong Park
Jaesung Choi
Ji-Yeob Choi
ResearchOpen Access17 Jun 2021
Scientific Reports

Volume: 11, P: 1-11
Reciprocal regulation of oxidative stress and mitochondrial fission augments parvalbumin downregulation through CDK5-DRP1- and GPx1-NF-κB signaling pathways

Su Hyeon Wang
Duk-Shin Lee
Tae-Cheon Kang
ResearchOpen Access30 Sept 2024
Cell Death & Disease

Volume: 15, P: 1-14
Differential diagnosis of common etiologies of left ventricular hypertrophy using a hybrid CNN-LSTM model

In-Chang Hwang
Dongjun Choi
Goo-Yeong Cho
ResearchOpen Access05 Dec 2022
Scientific Reports

Volume: 12, P: 1-12
Re-do Operation Using a Robotic System due to Locoregional Recurrence after Initial Thyroidectomy for Thyroid Cancer

Dong Gyu Kim
Kwangsoon Kim
Woong Youn Chung
ResearchOpen Access07 Jul 2022
Scientific Reports

Volume: 12, P: 1-9
Brush-paintable and highly stretchable Ag nanowire and PEDOT:PSS hybrid electrodes

Ji-Eun Lim
Sang-Mok Lee
Han-Ki Kim
ResearchOpen Access31 Oct 2017
Scientific Reports

Volume: 7, P: 1-12
CXCL12 enhances pregnancy outcome via improvement of endometrial receptivity in mice

Hwa Seon Koo
Min-Ji Yoon
Youn-Jung Kang
ResearchOpen Access01 Apr 2021
Scientific Reports

Volume: 11, P: 1-16
ANTXR2 is a potential causative gene in the genome-wide association study of the blood pressure locus 4q21

So Yon Park
Hyeon-Ju Lee
Bermseok Oh
Research17 Apr 2014
Hypertension Research

Volume: 37, P: 811-817
Human dopamine receptor nanovesicles for gate-potential modulators in high-performance field-effect transistor biosensors

Seon Joo Park
Hyun Seok Song
Jyongsik Jang
ResearchOpen Access11 Mar 2014
Scientific Reports

Volume: 4, P: 1-8
Proteomics-based identification and validation of novel plasma biomarkers phospholipid transfer protein and mannan-binding lectin serine protease-1 in age-related macular degeneration

Hye-Jung Kim
Seong Joon Ahn
Cheolju Lee
ResearchOpen Access08 Sept 2016
Scientific Reports

Volume: 6, P: 1-12
Long-term sentinel surveillance of enteroviruses in Gwangju, South Korea, 2011–2020

Min Ji Kim
Ji-eun Lee
Jin-jong Seo
ResearchOpen Access16 Feb 2023
Scientific Reports

Volume: 13, P: 1-11
Automated in-depth cerebral arterial labelling using cerebrovascular vasculature reframing and deep neural networks

Suk-Woo Hong
Ha-Na Song
Woo-Keun Seo
ResearchOpen Access24 Feb 2023
Scientific Reports

Volume: 13, P: 1-14
PDI augments kainic acid-induced seizure activity and neuronal death by inhibiting PP2A-GluA2-PICK1-mediated AMPA receptor internalization in the mouse hippocampus

Duk-Shin Lee
Tae-Hyun Kim
Ji-Eun Kim
ResearchOpen Access25 Aug 2023
Scientific Reports

Volume: 13, P: 1-16
Interannual fires as a source for subarctic summer decadal climate variability mediated by permafrost thawing

Ji-Eun Kim
Ryohei Yamaguchi
Malte F. Stuecker
ResearchOpen Access10 Jul 2023
npj Climate and Atmospheric Science

Volume: 6, P: 1-9
Glutamate dehydrogenase activator BCH stimulating reductive amination prevents high fat/high fructose diet-induced steatohepatitis and hyperglycemia in C57BL/6J mice

Seung Jin Han
Sung-E Choi
Yup Kang
ResearchOpen Access22 Nov 2016
Scientific Reports

Volume: 6, P: 1-13

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